Mirodzhov G K, Pavlov V L
Arkh Patol. 1991;53(4):72-6.
Morphological and functional features as well as cooperative relations of Kupffer's cells, endotheliocytes, lipocytes and pit-cells under normal and pathological conditions delineated in the literature are reviewed. It is shown that liver sinusoid cells protect the parenchyma, control hepatocyte regeneration, take part in the antitumor immunity, participate in the metabolism of lipids, lipoproteins, proteins, biogenic amines and collagen while the cooperative interaction between them and hepatocytes determines an interhepatic homeostasis.
本文综述了文献中所描述的正常和病理条件下库普弗细胞、内皮细胞、脂肪细胞和陷窝细胞的形态学和功能特征以及它们之间的合作关系。结果表明,肝窦细胞可保护实质细胞、控制肝细胞再生、参与抗肿瘤免疫、参与脂质、脂蛋白、蛋白质、生物胺和胶原蛋白的代谢,而它们与肝细胞之间的协同相互作用决定了肝脏内环境的稳定。