乳腺癌的临床特征——英日对比研究。

Clinical features of breast cancer--Anglo-Japanese comparative study.

作者信息

Miura S, Yoshida M, Murai H, Hayward J L, Chaudary M A

机构信息

Department of Breast Surgery, Aichi Cancer Center, Nagoya, Japan.

出版信息

Breast Cancer Res Treat. 1991 May;18 Suppl 1:S103-6. doi: 10.1007/BF02633539.

DOI:10.1007/BF02633539

PMID:1873544

Abstract

A comparative study was undertaken at Guy's Hospital in the UK and the Aichi Cancer Center in Japan of the clinical picture of breast cancer in the UK and Japan. Target patients were 221 UK and 200 Japanese primary operable patients who were recruited from April 1979 through August 1980. No difference was seen between the two countries in the side and site of the lesion and the size of the lesion. The localized tenderness of the tumor site was higher in Japanese patients than in UK patients (25.5% vs 0%). Difference was observed in tumor characteristics: breast cancers of the UK patients were irregular, ill-defined, and not so mobile, whereas those of the Japanese patients were round or oval, well-defined, and mobile. Skin fixation was higher in Japanese patients (71.0% vs 44.8%). Clinical node involvement was higher in UK patients (32.5% vs 19.0%).

摘要

英国盖伊医院和日本爱知癌症中心对英国和日本乳腺癌的临床情况进行了一项比较研究。目标患者为1979年4月至1980年8月招募的221名英国原发性可手术患者和200名日本原发性可手术患者。两国在病变的侧别、部位以及病变大小方面未见差异。日本患者肿瘤部位的局限性压痛高于英国患者（25.5%对0%）。在肿瘤特征方面观察到差异：英国患者的乳腺癌形态不规则、边界不清且活动度欠佳，而日本患者的乳腺癌呈圆形或椭圆形、边界清晰且活动度良好。日本患者的皮肤粘连情况更严重（71.0%对44.8%）。英国患者的临床淋巴结受累情况更严重（32.5%对19.0%）。