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英国和中国农村女性的血清激素水平。

Serum hormone levels in British and rural Chinese females.

作者信息

Wang D Y, Key T J, Pike M C, Boreham J, Chen J

机构信息

Imperial Cancer Research Fund, Radcliffe Infirmary, Oxford, UK.

出版信息

Breast Cancer Res Treat. 1991 May;18 Suppl 1:S41-5. doi: 10.1007/BF02633526.

DOI:10.1007/BF02633526
PMID:1873556
Abstract

The comparison of blood levels of oestradiol, testosterone, prolactin, and sex-hormone binding globulin (SHBG) was made of 3250 rural Chinese and 300 British women, aged 35 to 64. To reduce the number of assays performed the blood samples were combined so as to form 390 and 30 pools, respectively. The Chinese had significantly less oestradiol and testosterone. Prolactin levels were similar in both races. SHBG was significantly lower in postmenopausal British women. In the Chinese women, testosterone was positively and prolactin negatively correlated with breast cancer mortality.

摘要

对3250名年龄在35至64岁的中国农村女性和300名英国女性的雌二醇、睾酮、催乳素及性激素结合球蛋白(SHBG)的血液水平进行了比较。为减少检测次数,将血液样本合并,分别形成390组和30组样本池。中国人的雌二醇和睾酮水平显著较低。两个种族的催乳素水平相似。绝经后英国女性的SHBG水平显著较低。在中国女性中,睾酮与乳腺癌死亡率呈正相关,催乳素与乳腺癌死亡率呈负相关。

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本文引用的文献

1
Effects of obesity on sex steroid metabolism.肥胖对性类固醇代谢的影响。
J Chronic Dis. 1982;35(12):893-6. doi: 10.1016/0021-9681(82)90120-5.
2
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Circulating levels of testosterone, 17 beta-oestradiol, luteinising hormone and prolactin in postmenopausal breast cancer patients.绝经后乳腺癌患者体内睾酮、17β-雌二醇、促黄体生成素和催乳素的循环水平。
Br J Cancer. 1983 Feb;47(2):269-75. doi: 10.1038/bjc.1983.35.
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Androgen parameters and their correlation with body weight in one hundred thirty-eight women thought to have hyperandrogenism.138名被认为患有高雄激素血症的女性的雄激素参数及其与体重的相关性。
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The relationship between blood prolactin levels and risk of breast cancer in premenopausal women.绝经前女性血液中催乳素水平与患乳腺癌风险之间的关系。
Eur J Cancer Clin Oncol. 1987 Oct;23(10):1541-8. doi: 10.1016/0277-5379(87)90098-8.
10
The permanent effect of reproductive events on blood prolactin levels and its relation to breast cancer risk: a population study of postmenopausal women.生殖事件对血液催乳素水平的长期影响及其与乳腺癌风险的关系:一项绝经后女性的人群研究。
Eur J Cancer Clin Oncol. 1988 Jul;24(7):1225-31. doi: 10.1016/0277-5379(88)90132-0.