Wang D Y, Key T J, Pike M C, Boreham J, Chen J
Imperial Cancer Research Fund, Radcliffe Infirmary, Oxford, UK.
Breast Cancer Res Treat. 1991 May;18 Suppl 1:S41-5. doi: 10.1007/BF02633526.
The comparison of blood levels of oestradiol, testosterone, prolactin, and sex-hormone binding globulin (SHBG) was made of 3250 rural Chinese and 300 British women, aged 35 to 64. To reduce the number of assays performed the blood samples were combined so as to form 390 and 30 pools, respectively. The Chinese had significantly less oestradiol and testosterone. Prolactin levels were similar in both races. SHBG was significantly lower in postmenopausal British women. In the Chinese women, testosterone was positively and prolactin negatively correlated with breast cancer mortality.
对3250名年龄在35至64岁的中国农村女性和300名英国女性的雌二醇、睾酮、催乳素及性激素结合球蛋白(SHBG)的血液水平进行了比较。为减少检测次数,将血液样本合并,分别形成390组和30组样本池。中国人的雌二醇和睾酮水平显著较低。两个种族的催乳素水平相似。绝经后英国女性的SHBG水平显著较低。在中国女性中,睾酮与乳腺癌死亡率呈正相关,催乳素与乳腺癌死亡率呈负相关。