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雌二醇和孕酮对大鼠子宫核糖核酸酶抑制活性的影响。

Effects of estradiol and progesterone on rat uterine ribonuclease inhibitor activity.

作者信息

Schauer R C

机构信息

Biology Department, Gannon University, Erie, Pennsylvania.

出版信息

Horm Metab Res. 1991 Apr;23(4):162-5. doi: 10.1055/s-2007-1003641.

DOI:10.1055/s-2007-1003641
PMID:1874473
Abstract

The effects of estradiol (E2) and progesterone on rat uterine RNase inhibitor activity were investigated. RNase inhibitor activity was found to be most prominent in nuclear and cytosolic fractions of the uterus. Uterine RNase inhibitor activity in the 45,000 x g cytosolic fraction was stimulated by E2 over a 6-24 hr treatment period. Progesterone did not produce a significant change in the uterine cytosolic RNase inhibitor activity during the same period.

摘要

研究了雌二醇(E2)和孕酮对大鼠子宫核糖核酸酶抑制剂活性的影响。发现核糖核酸酶抑制剂活性在子宫的核和胞质部分最为显著。在6 - 24小时的处理期内,E2刺激了45,000 x g胞质部分的子宫核糖核酸酶抑制剂活性。在同一时期,孕酮未使子宫胞质核糖核酸酶抑制剂活性产生显著变化。

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