Sargent B J, Gough D A
Department of Applied Mechanics and Engineering Sciences, University of California, San Diego, La Jolla 92093.
IEEE Trans Biomed Eng. 1991 May;38(5):476-82. doi: 10.1109/10.81567.
A new oxygen monitoring system has been developed that consists of an array of transparent, independently-connected oxygen sensors mounted on a glass plate. This system is intended for continuous monitoring of oxygen at multiple locations on the surface of exteriorized tissues, while simultaneously visualizing microvascular activity. The sensor array is fabricated by techniques similar to those employed for semiconductors, which facilitate customization of sensor size and pattern to best monitor oxygen in a given physiologic preparation. Methods are described for characterizing the performance of the sensor array in vitro, including studies on the oxygen sensitivity, stability of the signal, and detection of oxygen gradients. An example of in vivo application of the sensor array is also presented.
一种新的氧监测系统已经研发出来，它由安装在玻璃板上的一系列透明、独立连接的氧传感器组成。该系统旨在连续监测外露组织表面多个位置的氧气，同时可视化微血管活动。传感器阵列采用与半导体制造技术类似的技术制造，这便于根据给定生理制剂的最佳监测氧气情况定制传感器的尺寸和图案。文中描述了在体外表征传感器阵列性能的方法，包括对氧敏感性、信号稳定性以及氧梯度检测的研究。还给出了传感器阵列在体内应用的一个例子。
