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中国内蒙古蒙古族人群中高血压前期与高血压患者心血管危险因素的比较

Comparison of cardiovascular risk factors between prehypertension and hypertension in a Mongolian population, Inner Mongolia, China.

作者信息

Li Hongmei, Xu Tan, Tong Weijun, Liu Yanbin, Zhao Li, Zhang Yonghong

机构信息

Department of Epidemiology, Soochow University School of Radiation Medicine and Public Health, Suzhou, China.

出版信息

Circ J. 2008 Oct;72(10):1666-73. doi: 10.1253/circj.cj-08-0138. Epub 2008 Aug 28.

DOI:10.1253/circj.cj-08-0138
PMID:18753701
Abstract

BACKGROUND

There is little knowledge on comparisons of cardiovascular risk factors between prehypertension and hypertension in Mongolian populations, Inner Mongolia, China.

METHODS AND RESULTS

A total of 2,589 Mongolians aged 20 years and over were recruited as study participants. Demographic data, lifestyle factors, family history of hypertension, blood pressure measurements, physical examination and blood samples were obtained and analyzed for all individuals. Prehypertensives and hypertensives accounted for 38.39% and 37.39%, respectively, in all participants. Multivariate logistic regression using proportional odds model showed that hypertension was significantly associated with age (odds ratio was 5.79, 8.84, 30.05 and 32.28 for age 40-, 50-, 60- and 70-, respectively), family history of hypertension (7.12), alcohol drinking (2.03), overweight (4.69) and hyperlipidemia (3.49), and prehypertension significantly associated with age (3.65 for age 70-84), hyperlipidemia (1.80) in males. In females, hypertension was significantly associated with age (8.58, 14.40, 33.00, 63.67 for age 40-, 50-, 60- and 70-, respectively), family history of hypertension (5.65), overweight (3.16) and high C-reactive protein (> or = 10.356 mg/L), and prehypertension significantly associated with age (1.72, 2.00, 2.74 and 6.67 for age 40-, 50-, 60- and 70-, respectively) and overweight (1.68).

CONCLUSIONS

Prevalence of some cardiovascular risk factors and number of risk factors in hypertensives were higher than that in prehypertensives.

摘要

背景

在中国内蒙古蒙古族人群中,关于高血压前期与高血压患者心血管危险因素对比的研究较少。

方法与结果

共招募了2589名年龄在20岁及以上的蒙古族作为研究对象。收集了所有个体的人口统计学数据、生活方式因素、高血压家族史、血压测量值、体格检查结果及血液样本并进行分析。在所有参与者中,高血压前期和高血压患者分别占38.39%和37.39%。采用比例优势模型进行多因素逻辑回归分析显示,高血压与年龄(40、50、60和70岁人群的比值比分别为5.79、8.84、30.05和32.28)、高血压家族史(7.12)、饮酒(2.03)、超重(4.69)及高脂血症(3.49)显著相关;在男性中,高血压前期与年龄(70 - 84岁人群为3.65)、高脂血症(1.80)显著相关。在女性中,高血压与年龄(4

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