Groeneveld J H M, van Buren M, van Overhagen H
HagaZiekenhuis, locatie Leyenburg, Leyweg 275, 2545 CH Den Haag.
Ned Tijdschr Geneeskd. 2008 Aug 9;152(32):1789-93.
In three women on chronic haemodialysis because of end-stage renal disease who were 40, 59, and 73 years of age respectively, spontaneous renal bleeding was diagnosed. The first two patients presented with acute flank pain and signs of sudden blood loss, the third one had chronic abdominal pain and anaemia. A CT scan demonstrated perirenal bleeding in all three patients and expansion into the retroperitoneal space in the first and third patient. In the latter two patients, acquired renal cysts had been visible during earlier abdominal ultrasound. None of the patients had severe hypertension, but all of them had received medication enhancing bleeding tendency, such as nadroparin, which was administered during haemodialysis. The first and the last patient were treated conservatively and survived. The second patient was haemodynamically unstable and underwent embolisation to stop the bleeding. She died in hospital after fifteen days due to the complications of a cardiac arrest. Abdominal CT or ultrasound is the technique of choice to evaluate patients with end-stage renal disease with loin pain or bleeding. Most of the time, conservative treatment suffices.
在三名分别为40岁、59岁和73岁的因终末期肾病接受慢性血液透析的女性患者中,诊断出自发性肾出血。前两名患者表现为急性腰痛和急性失血迹象,第三名患者有慢性腹痛和贫血。CT扫描显示所有三名患者均有肾周出血,第一名和第三名患者的出血扩展至腹膜后间隙。在后两名患者中,早期腹部超声检查可见获得性肾囊肿。所有患者均无严重高血压,但均接受过增强出血倾向的药物治疗,如血液透析期间使用的那屈肝素。第一名和最后一名患者接受了保守治疗并存活下来。第二名患者血流动力学不稳定,接受了栓塞治疗以止血。她在15天后因心脏骤停并发症死于医院。腹部CT或超声是评估有腰痛或出血的终末期肾病患者的首选技术。大多数情况下,保守治疗就足够了。