Cumurcu Tongabay, Kilic Rasit, Yologlu Saim
Department of Ophthalmology, Inonu University School of Medicine, Malatya, Turkey.
Eur J Ophthalmol. 2010 Nov-Dec;20(6):1007-11. doi: 10.1177/112067211002000621.
To assess the frequency of pseudoexfoliation syndrome (PEX) and evaluate its association with specific ocular diseases in patients attending the Department of Ophthalmology at Gaziosmanpasa University Hospital.
A prospective study was conducted at the Gaziosmanpasa University Hospital between December 2007 and December 2008. A total of 831 subjects aged 45 or above attending the general ophthalmic clinics were recruited for this study. Each patient underwent complete ophthalmic assessment, including ocular history, visual acuity testing, slit-lamp examination, applanation tonometry, gonioscopy, and fundus examination.
Of the 831 subjects, 12.2% had PEX. Pseudoexfoliation was bilateral in 74.2% of cases, significantly associated with cataract, glaucoma, age-related macular degeneration (AMD), and phacodenesis. Of the patients with PEX, 43.6% had cataract, 6.9% had glaucoma, 7.9% had AMD, and 0.9% had phacodenesis. In addition, 9.8% had cataract + glaucoma, 13.7% had cataract + phacodenesis, and 17.8% had all of them. The prevalence of PEX had a tendency to increase with age but had no sex predilection.
The study findings enhance our knowledge of PEX in Anatolia, particularly in the Middle Black Sea region.
评估假性剥脱综合征（PEX）的发生率，并评价其与加济奥斯曼帕夏大学医院眼科就诊患者特定眼部疾病的相关性。
于2007年12月至2008年12月在加济奥斯曼帕夏大学医院进行了一项前瞻性研究。本研究共纳入831名年龄在45岁及以上的普通眼科门诊患者。每位患者均接受了全面的眼科评估，包括眼部病史、视力测试、裂隙灯检查、压平眼压测量、前房角镜检查和眼底检查。
在831名受试者中，12.2%患有PEX。74.2%的病例中PEX为双侧性，与白内障、青光眼、年龄相关性黄斑变性（AMD）和晶状体不全显著相关。在患有PEX的患者中，43.6%患有白内障，6.9%患有青光眼，7.9%患有AMD，0.9%患有晶状体不全。此外，9.8%患有白内障+青光眼，13.7%患有白内障+晶状体不全，17.8%患有所有这些疾病。PEX的患病率有随年龄增加的趋势，但无性别倾向。
该研究结果增进了我们对安纳托利亚地区，特别是中黑海地区PEX的认识。
