Yibekal Betelhem Temesgen, Adimassu Nebiyat Feleke, Ayele Fisseha Admassu
Department of Optometry, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar City, Ethiopia.
Department of Ophthalmology, School of Medicine, College of Medicine and Health Science, University of Gondar, Gondar City, Ethiopia.
Clin Optom (Auckl). 2021 Aug 24;13:249-255. doi: 10.2147/OPTO.S321716. eCollection 2021.
Pseudoexfoliation syndrome is an age-related disorder characterized by the deposition of a distinct fibrillar extracellular material in various tissues and organs of the body. Glaucoma and cataract are the consistently reported clinical consequences of Pseudoexfoliation syndrome on the eye. This study aimed to estimate the proportion of pseudo-exfoliation syndrome and associated factors in Gondar university comprehensive specialized hospital tertiary eye care and training center.
Institution-based cross-sectional study was conducted from January to March 2019 at Gondar university comprehensive specialized hospital tertiary eye care and training center among 295 patients. Consecutive 295 participants aged above 40 years were involved in the study. A structured questionnaire and ocular examination were used to collect the data. Data were entered into EPI-INFO 3.5.1 and exported to SPSS version 20 for analysis. Factors associated with pseudoexfoliation syndrome were ascertained by chi-square and independent -test. Statistical significance was considered when p-value <0.05.
A total of 295 adults participated in the study with a response rate of 92.8%. The median (±IQR) age of study respondents was 64(±9) years and 67.8% were males. The proportion pseudoexfoliation syndrome was 34.6% [95% CI: 29.2-40.7%]. The mean IOP and mean age were significantly higher among patients with pseudoexfoliation syndrome. Age, sex, high IOP, glaucoma, outdoor work, and rural residence were significantly associated with the proportion of pseudoexfoliation syndrome.
The proportion of pseudoexfoliation syndrome among participants aged ≥40 years was high. Age, sex, high IOP, glaucoma, outdoor work, and rural residence were factors having a significant association with the proportion of pseudoexfoliation syndrome.
假性剥脱综合征是一种与年龄相关的疾病，其特征是在身体的各种组织和器官中沉积一种独特的纤维状细胞外物质。青光眼和白内障是假性剥脱综合征对眼睛持续报道的临床后果。本研究旨在估计贡德尔大学综合专科医院三级眼科护理和培训中心假性剥脱综合征的比例及相关因素。
2019年1月至3月在贡德尔大学综合专科医院三级眼科护理和培训中心对295例患者进行了基于机构的横断面研究。连续纳入295名年龄在40岁以上的参与者。使用结构化问卷和眼部检查收集数据。数据录入EPI-INFO 3.5.1并导出到SPSS 20版进行分析。通过卡方检验和独立样本t检验确定与假性剥脱综合征相关的因素。当p值<0.05时认为具有统计学意义。
共有295名成年人参与研究，应答率为92.8%。研究对象的年龄中位数（±四分位间距）为64（±9）岁，男性占67.8%。假性剥脱综合征的比例为34.6%[95%置信区间：29.2 - 40.7%]。假性剥脱综合征患者的平均眼压和平均年龄显著更高。年龄、性别、高眼压、青光眼、户外工作和农村居住与假性剥脱综合征的比例显著相关。
40岁及以上参与者中假性剥脱综合征的比例较高。年龄、性别、高眼压、青光眼、户外工作和农村居住是与假性剥脱综合征比例有显著关联的因素。
