Dretler S P, Bhatta K M, Rosen D
Department of Urology, Massachusetts General Hospital, Boston.
J Urol. 1991 Sep;146(3):746-50. doi: 10.1016/s0022-5347(17)37911-9.
A 3.3F electrohydraulic electrode (Wolf 2137.23) has been confined within a spring with a metal end cap, irrigated with water and covered with a 0.003-inch metal sheath (outside diameter 5F). The electrohydraulic lithotripsy discharge (Wolf Generator 2137.50) at E1 causes the metal cap to extend 3 mm. at 1,500 cm. per second and creates an impact pressure of 600 to 800 bar. Stone fragmentation efficiency of the electromechanical impactor was equivalent to unshielded electrohydraulic lithotripsy (gallstone 2.83 mg. per pulse, struvite/apatite 1.41 mg. per pulse, cystine 0.41 mg. per pulse, uric acid 1.48 mg. per pulse and 100% calcium oxalate monohydrate 0.10 mg. per pulse). Studies of the discharge of the electromechanical impactor within the pig ureter showed that minimal ureteral submucosal edema and hemorrhage occurred at 300 shocks discharged at a single point, and disruption of the mucosa and partial injury to the muscle layer occurred after 600 shocks given at the site of a pinched pig ureter. Pushing the electromechanical impactor perpendicular to the wall of the pig bladder will create a mechanical perforation within 35 shocks (electrohydraulic lithotripsy within 2 shocks). One patient had excellent fragmentation of a lower ureteral mixed monohydrate and dihydrate stone under direct vision performed with the electromechanical impactor passed via a 9.5F ureteroscope. There was no evidence of mucosal injury with 500 shocks. The electromechanical impactor has been developed to provide a safe and inexpensive method of ureteral stone fragmentation or disimpaction. These studies were performed to establish limits of safety that may allow use of the electromechanical impactor for stone fragmentation in the ureter without the need for ureteroscopy.
一个3.3F的电动液压电极(Wolf 2137.23)被封闭在一个带有金属端盖的弹簧内,用水冲洗,并覆盖有一个0.003英寸的金属护套(外径5F)。电动液压碎石放电(Wolf发生器2137.50)在E1时使金属帽以每秒1500厘米的速度伸出3毫米,并产生600至800巴的冲击压力。机电冲击器的结石破碎效率与未屏蔽的电动液压碎石术相当(胆结石每脉冲2.83毫克,鸟粪石/磷灰石每脉冲1.41毫克,胱氨酸每脉冲0.41毫克,尿酸每脉冲1.48毫克,100%一水合草酸钙每脉冲0.10毫克)。对猪输尿管内机电冲击器放电的研究表明,在单点放电300次时,输尿管黏膜下水肿和出血最少,在猪输尿管狭窄部位给予600次冲击后,黏膜破裂和肌层部分损伤。将机电冲击器垂直于猪膀胱壁推压,在35次冲击内会造成机械穿孔(电动液压碎石术在2次冲击内)。一名患者在直视下用通过9.5F输尿管镜插入的机电冲击器对输尿管下段的一水合和二水合混合结石进行了出色的破碎。500次冲击后没有黏膜损伤的迹象。机电冲击器的开发是为了提供一种安全且廉价的输尿管结石破碎或取出方法。进行这些研究是为了确定安全限度,以便在不需要输尿管镜检查的情况下,能够使用机电冲击器进行输尿管结石破碎。