Savadi-Oskouei Daryoush, Abedi Ali, Sadeghi-Bazargani Homayoun
Neuroscience Research Center, Faculty of Medicine, Tabriz University, Tabriz, Iran.
Eur Neurol. 2008;60(5):253-7. doi: 10.1159/000151701. Epub 2008 Aug 29.
BACKGROUND/AIM: In this case-control study, our aim was to check for a possible independent role of hypertension in increasing the risk of developing Bell's palsy.
All patients diagnosed as having Bell's palsy referred to a neurology clinic were enrolled as cases. Controls were selected among other patients referred to the same clinic. Data were analyzed using the Stata 8 statistical software package. To detect the independent effect of exposure variables, a multiple logistic regression test was used.
Bivariate analysis showed an increased risk of Bell's palsy for patients with diabetes or hypertension. Logistic regression results stratified for patients younger than 40 years of age and others showed that diabetes was the independent predictor of Bell's palsy in both age groups. Logistic regression results showed that hypertension could not independently predict the occurrence of Bell's palsy among patients younger than 40 years but for older ones it could.
Hypertension may increase the risk of Bell's palsy among those aged above 40 years. Researchers should be very cautious when declaring an independent role of hypertension as a cause of Bell's palsy.
背景/目的:在这项病例对照研究中,我们的目的是检验高血压在增加贝尔麻痹发病风险方面是否可能具有独立作用。
所有被诊断为贝尔麻痹并转诊至神经科门诊的患者被纳入病例组。对照组从转诊至同一门诊的其他患者中选取。使用Stata 8统计软件包对数据进行分析。为检测暴露变量的独立效应,采用了多元逻辑回归检验。
双变量分析显示,糖尿病或高血压患者患贝尔麻痹的风险增加。对40岁及以下患者和其他患者进行分层的逻辑回归结果表明,糖尿病在两个年龄组中都是贝尔麻痹的独立预测因素。逻辑回归结果显示,高血压不能独立预测40岁及以下患者贝尔麻痹的发生,但对年龄较大的患者可以。
高血压可能会增加40岁以上人群患贝尔麻痹的风险。在宣称高血压作为贝尔麻痹病因的独立作用时,研究人员应非常谨慎。