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rel基因产物在控制环磷酸腺苷积累中的作用。

Role of the rel gene product in the control of cyclic adenosine 3',5'-monophosphate accumulation.

作者信息

Braedt G, Gallant J

出版信息

J Bacteriol. 1977 Jan;129(1):564-6. doi: 10.1128/jb.129.1.564-566.1977.

Abstract

The presence of a relA mutant allele affects the kinetics of cyclic adenosine 3',5'-monophosphate accumulation during downshift from glucose to succinate. The nucleotide accumulates at the normal rate early in the downshift transition but continues to accumulate for a longer time in the relA mutant, leading to a two- to threefold excess by the end of the diauxic lag. Evidence is presented that this effect occurs independently of the accumulation of ppGpp.

摘要

relA突变等位基因的存在会影响从葡萄糖向琥珀酸转换过程中3',5'-环磷酸腺苷积累的动力学。在转换初期,核苷酸以正常速率积累,但在relA突变体中会持续积累更长时间,导致在二次生长停滞结束时积累量多出两到三倍。有证据表明,这种效应的发生与ppGpp的积累无关。

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Cyclic adenosine 3',5'-monophosphate in Escherichia coli.大肠杆菌中的环腺苷酸3',5'-单磷酸
J Bacteriol. 1973 Jun;114(3):1068-73. doi: 10.1128/jb.114.3.1068-1073.1973.
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Cyclic adenosine monophosphate in bacteria.细菌中的环磷酸腺苷
Science. 1970 Jul 24;169(3943):339-44. doi: 10.1126/science.169.3943.339.

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