Bragheeth M A, Fares U, Dua H S
Division of Ophthalmology and Visual Sciences, B Floor, Eye Ear Nose Throat Centre, University Hospital, Queen's Medical Centre, Nottingham, UK.
Br J Ophthalmol. 2008 Nov;92(11):1506-10. doi: 10.1136/bjo.2008.143636. Epub 2008 Aug 29.
To evaluate the results of laser in situ keratomileusis (LASIK) re-treatment for under correction or regression after primary LASIK procedures for myopia and myopic astigmatism.
A prospective evaluation of 360 consecutive LASIK-treated eyes, for myopia and/or myopic astigmatism, 32 eyes of 34 patients were retreated and followed at 3, 6 and 12 months post-retreatment. Re-treatment was performed by lifting the original flap after cutting the epithelium around the flap edge with a fine needle. Standard ablation was performed based on the patient's residual refraction.
9.4% of eyes required retreatment. Prior to re-treatment the mean manifest spherical equivalent (SE) was -0.99 (SD 1.48) D (range -0.75 to -2.63). The mean sphere was -0.79 (1.20) D (range -2.50 to -0.50), and the mean cylinder was -0.90 D (1.14) D (from -2.75 to 1.25). At 1-year follow-up 56% of the eyes were within +/-0.50 D SE, and 78% were within +/-1.00 D SE. 78% of the eyes examined at 1-year post-re-treatment managed unaided vision of 6/9 or better. Peripheral epithelial ingrowth not requiring treatment developed in two eyes. Second re-treatment for regression was performed in one eye. A significant correlation was found between the refractive regression and each of the following: preoperative refraction, attempted correction and ablation depth.
LASIK re-treatment for residual myopia, by lifting the original flap, is an effective option. Refractive results are fairly predictable, and refraction stabilises by 3 months after re-treatment. Lifting the corneal flap after cutting the epithelium on the flap edges is easy to perform and has a very low incidence of epithelial ingrowth.
评估准分子原位角膜磨镶术(LASIK)再次治疗近视及近视散光初次LASIK术后欠矫或回退的效果。
对360例连续接受LASIK治疗的近视和/或近视散光眼进行前瞻性评估,34例患者的32只眼接受了再次治疗,并在再次治疗后3、6和12个月进行随访。用细针在瓣边缘周围切开上皮后掀起原瓣进行再次治疗。根据患者的残余屈光度进行标准切削。
9.4%的眼需要再次治疗。再次治疗前平均明显球镜等效度(SE)为-0.99(标准差1.48)D(范围-0.75至-2.63)。平均球镜为-0.79(1.20)D(范围-2.50至-0.50),平均柱镜为-0.90 D(1.14)D(范围-2.75至1.25)。在1年随访时,56%的眼SE在±0.50 D以内,78%的眼SE在±1.00 D以内。再次治疗后1年检查的眼中有78%的裸眼视力达到6/9或更好。2只眼出现了无需治疗的周边上皮内生。1只眼因回退进行了二次再次治疗。屈光回退与以下各项均存在显著相关性:术前屈光度、预期矫正量和切削深度。
通过掀起原瓣对残余近视进行LASIK再次治疗是一种有效的选择。屈光结果相当可预测,再次治疗后3个月屈光稳定。在瓣边缘切开上皮后掀起角膜瓣操作简便,上皮内生发生率极低。