在接触石棉的工人中，动脉粥样硬化和胸膜钙化是相关的。
Atherosclerotic and pleural calcifications are related among asbestos-exposed workers.
作者信息
Vehmas Tapio, Hiltunen Asta, Kivisaari Leena, Leino-Arjas Päivi
机构信息
Health and Work Ability, Finnish Institute of Occupational Health, Topeliuksenkatu 41 a A, FIN-00250 Helsinki, Finland.
出版信息
Eur J Cardiovasc Prev Rehabil. 2008 Oct;15(5):599-601. doi: 10.1097/HJR.0b013e328309a224.
METHODS
We studied the relationship between calcified chest atherosclerosis and pleural plaques among 505 construction workers with computed tomography. The extent and thickness of pleural plaques and the score of visceral pleural thickening were estimated, as was calcification of both pleural disease and chest atherosclerosis.
RESULTS
Adjusted for age, BMI, smoking, and asbestos exposure, pleural calcification was associated with calcification in coronary arteries (P<0.001) and in the aorta (P<0.001).
CONCLUSION
These associations may be due to susceptibility factors common to both conditions. Calcification in pleural plaques may be a hint of atherosclerosis at least among asbestos-exposed people.
方法
我们利用计算机断层扫描研究了505名建筑工人的钙化性胸段动脉粥样硬化与胸膜斑之间的关系。评估了胸膜斑的范围和厚度以及脏层胸膜增厚的评分，同时也评估了胸膜疾病和胸段动脉粥样硬化的钙化情况。
结果
在对年龄、体重指数、吸烟和石棉暴露进行校正后，胸膜钙化与冠状动脉钙化（P<0.001）和主动脉钙化（P<0.001）相关。
结论
这些关联可能归因于两种情况共有的易感性因素。胸膜斑钙化可能至少在石棉暴露人群中提示动脉粥样硬化。
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