朊病毒：疾病还是救赎？
Prion: disease or relief?
作者信息
Chernoff Yury O
机构信息
School of Biology and Institute for Bioengineering and Bioscience, Georgia Institute of Technology, 310 Ferst Drive, Atlanta, GA 30332-0230, USA.
出版信息
Nat Cell Biol. 2008 Sep;10(9):1019-21. doi: 10.1038/ncb0908-1019.
PMID:18758490
Abstract
The self-perpetuating amyloid isoform, or prion, of the yeast translation termination factor eRF3 modulates programmed translational frameshifting that controls a regulatory circuit determining the polyamine levels in a yeast cell. But it is still unclear whether this effect is adaptive or pathological.
摘要
酵母翻译终止因子eRF3的自我延续性淀粉样异构体或朊病毒，可调节程序性翻译移码，该移码控制着一个决定酵母细胞中多胺水平的调节回路。但这种效应是适应性的还是病理性的仍不清楚。
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