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[中风中的运动障碍]

[Movement disorders in stroke].

作者信息

Ghika J

机构信息

Service de neurologie, CHUV, Lausanne, Suisse.

出版信息

Rev Neurol (Paris). 2008 Oct;164(10):833-6. doi: 10.1016/j.neurol.2008.07.013. Epub 2008 Aug 28.

Abstract

Dyskinesias are infrequent presentations in acute stroke (1%). They can be found more frequently as delayed presentations after a stroke, but the prevalence is not available from the literature. The full spectrum of hyper- and hypo-akinetic syndromes has been described, but three main pictures are rather specific of an acute stroke: limb shaking, hemichorea-hemiballism and unilateral asterixis. Besides limb shaking, that seems to reflect a transient diffuse ischemia of the frontosubcortical motor pathway, lesions are described at all levels of the frontosubcortical motor circuit including the sensorimotor frontoparietal cortex, the striatum, the pallidum, the thalamic nuclei, the subthalamic nucleus, the substantia nigra, the cerebellum, the brainstem and their interconnecting pathways, as ischemic or hemorrhagic strokes. The preferentially late development of dyskinesia could reflect the return to a more ancestral motor control level, the most functional possible with the remaining configuration of structures, elaborated by brain plasticity after stroke.

摘要

运动障碍在急性卒中中并不常见(发生率为1%)。它们在卒中后作为延迟表现更为常见,但文献中未提及其患病率。已经描述了各种运动过多和运动过少综合征,但急性卒中的三种主要表现相当具有特异性:肢体抖动、偏侧舞蹈症-偏侧投掷症和单侧扑翼样震颤。除了肢体抖动似乎反映了额皮质下运动通路的短暂性弥漫性缺血外,包括感觉运动性额顶叶皮质、纹状体、苍白球、丘脑核、底丘脑核、黑质、小脑、脑干及其相互连接通路在内的额皮质下运动回路的各个层面都有病变描述,病变类型包括缺血性或出血性卒中。运动障碍优先在后期出现,这可能反映了恢复到更为原始的运动控制水平,即由卒中后脑可塑性对剩余结构配置所形成的最具功能的水平。

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