减肥外科医生的最佳领域。

A sweet spot for the bariatric surgeon.

作者信息

Perez-Tilve Diego, D'Alessio David A, Tschöp Matthias H

机构信息

Departments of Psychiatry and Medicine, Obesity Research Centre, University of Cincinnati School of Medicine, Cincinnati, OH 45267, USA.

出版信息

Cell Metab. 2008 Sep;8(3):177-9. doi: 10.1016/j.cmet.2008.08.012.

DOI:10.1016/j.cmet.2008.08.012

PMID:18762016

Abstract

While gastric bypass surgery remains popular as the only treatment for morbid obesity with curative potential, the molecular mechanisms underpinning its immediate metabolic benefits remain unclear. New work in this issue (Troy et al., 2008) suggests intestinal glucose production sensed by afferent nerve fibers surrounding the portal vein may be key.

摘要

尽管胃旁路手术作为唯一具有治愈潜力的病态肥胖治疗方法仍然很受欢迎，但其直接代谢益处背后的分子机制仍不清楚。本期的一项新研究（Troy等人，2008年）表明，门静脉周围传入神经纤维感知到的肠道葡萄糖生成可能是关键。