Perez-Tilve Diego, D'Alessio David A, Tschöp Matthias H
Departments of Psychiatry and Medicine, Obesity Research Centre, University of Cincinnati School of Medicine, Cincinnati, OH 45267, USA.
Cell Metab. 2008 Sep;8(3):177-9. doi: 10.1016/j.cmet.2008.08.012.
While gastric bypass surgery remains popular as the only treatment for morbid obesity with curative potential, the molecular mechanisms underpinning its immediate metabolic benefits remain unclear. New work in this issue (Troy et al., 2008) suggests intestinal glucose production sensed by afferent nerve fibers surrounding the portal vein may be key.
尽管胃旁路手术作为唯一具有治愈潜力的病态肥胖治疗方法仍然很受欢迎，但其直接代谢益处背后的分子机制仍不清楚。本期的一项新研究（Troy等人，2008年）表明，门静脉周围传入神经纤维感知到的肠道葡萄糖生成可能是关键。
