Tomlinson F H, Scheithauer B W, Kelly P J, Forbes G S
Department of Neurosurgery, Mayo Clinic, Rochester, Minnesota.
Neurosurgery. 1991 May;28(5):761-8.
A unique gliomesenchymal neoplasm, consisting of a subependymoma, a form of low-grade glioma, and a rhabdomyosarcoma, is described. It arose and recurred in the brain stem of a 52-year-old man. Immunohistochemical studies demonstrated the presence of a neuroectodermal marker S-100 protein within some sarcoma cells. The occurrence of this rare tumor supports the concept that striated muscle may derive from a neuroectodermal precursor lesion.
描述了一种独特的胶质间叶肿瘤，它由室管膜下瘤（一种低级别胶质瘤）和横纹肌肉瘤组成。该肿瘤发生于一名52岁男性的脑干，并出现复发。免疫组织化学研究显示，部分肉瘤细胞内存在神经外胚层标志物S-100蛋白。这种罕见肿瘤的发生支持了横纹肌可能起源于神经外胚层前体病变的观点。
