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儿童头痛的补充和替代疗法。

Complementary and alternative treatments for childhood headaches.

作者信息

Tepper Stewart J

机构信息

Center for Headache and Pain, T33, Neurological Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA.

出版信息

Curr Pain Headache Rep. 2008 Oct;12(5):379-83. doi: 10.1007/s11916-008-0064-8.

DOI:10.1007/s11916-008-0064-8
PMID:18765145
Abstract

Parents frequently ask health care professionals to provide "natural" migraine care for their children and often use herbs, minerals, vitamins, and supplements to treat their children's migraines, thinking that these over-the-counter alternatives are less toxic than prescription medications. The only randomized controlled trial on any alternative treatment for pediatric migraine is for magnesium, and the results were equivocal. Results of two other uncontrolled trials of magnesium, one for migraine and one for episodic tension-type headache, were positive. There is one positive uncontrolled trial each for coenzyme Q10 and Petasites for prevention of pediatric migraine. There are no trials to indicate the safety or efficacy of riboflavin or feverfew for pediatric headache.

摘要

家长们经常要求医疗保健专业人员为他们的孩子提供“天然”的偏头痛治疗方法,并且常常使用草药、矿物质、维生素和补充剂来治疗孩子的偏头痛,他们认为这些非处方替代品的毒性低于处方药。关于小儿偏头痛任何替代疗法的唯一一项随机对照试验是针对镁的,结果并不明确。另外两项关于镁的非对照试验,一项针对偏头痛,一项针对发作性紧张型头痛,结果是阳性的。辅酶Q10和蜂斗菜用于预防小儿偏头痛各有一项阳性非对照试验。没有试验表明核黄素或小白菊对小儿头痛的安全性或有效性。

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Korean J Pain. 2017 Jul;30(3):176-182. doi: 10.3344/kjp.2017.30.3.176. Epub 2017 Jun 30.
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Preventive drugs in childhood and adolescent migraine.

本文引用的文献

1
Magnesium as a preventive treatment for paediatric episodic tension-type headache: results at 1-year follow-up.镁作为小儿发作性紧张型头痛的预防性治疗:1年随访结果
Neurol Sci. 2007 Jun;28(3):148-50. doi: 10.1007/s10072-007-0808-y. Epub 2007 Jun 30.
2
Coenzyme Q10 deficiency and response to supplementation in pediatric and adolescent migraine.儿童和青少年偏头痛中的辅酶Q10缺乏症及补充治疗反应
Headache. 2007 Jan;47(1):73-80. doi: 10.1111/j.1526-4610.2007.00652.x.
3
Efficacy and safety of 6.25 mg t.i.d. feverfew CO2-extract (MIG-99) in migraine prevention--a randomized, double-blind, multicentre, placebo-controlled study.
儿童和青少年偏头痛的预防性药物
Curr Pain Headache Rep. 2014 Jun;18(6):422. doi: 10.1007/s11916-014-0422-7.
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Riboflavin prophylaxis in pediatric and adolescent migraine.儿童和青少年偏头痛的核黄素预防
J Headache Pain. 2009 Oct;10(5):361-5. doi: 10.1007/s10194-009-0142-2. Epub 2009 Aug 1.
每日三次服用6.25毫克小白菊二氧化碳提取物(MIG-99)预防偏头痛的疗效与安全性——一项随机、双盲、多中心、安慰剂对照研究
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Migraine prevention in children and adolescents: results of an open study with a special butterbur root extract.儿童和青少年偏头痛的预防:一项使用特种款冬根提取物的开放性研究结果
Headache. 2005 Mar;45(3):196-203. doi: 10.1111/j.1526-4610.2005.05044.x.
5
Efficacy of coenzyme Q10 in migraine prophylaxis: a randomized controlled trial.辅酶Q10预防偏头痛的疗效:一项随机对照试验。
Neurology. 2005 Feb 22;64(4):713-5. doi: 10.1212/01.WNL.0000151975.03598.ED.
6
Petasites hybridus root (butterbur) is an effective preventive treatment for migraine.蜂斗菜根(款冬)是偏头痛的一种有效预防性治疗方法。
Neurology. 2004 Dec 28;63(12):2240-4. doi: 10.1212/01.wnl.0000147290.68260.11.
7
A combination of riboflavin, magnesium, and feverfew for migraine prophylaxis: a randomized trial.核黄素、镁和小白菊联合用于偏头痛预防:一项随机试验。
Headache. 2004 Oct;44(9):885-90. doi: 10.1111/j.1526-4610.2004.04170.x.
8
Oral magnesium oxide prophylaxis of frequent migrainous headache in children: a randomized, double-blind, placebo-controlled trial.口服氧化镁预防儿童频繁偏头痛性头痛:一项随机、双盲、安慰剂对照试验。
Headache. 2003 Jun;43(6):601-10. doi: 10.1046/j.1526-4610.2003.03102.x.
9
The efficacy and safety of Tanacetum parthenium (feverfew) in migraine prophylaxis--a double-blind, multicentre, randomized placebo-controlled dose-response study.小白菊用于偏头痛预防的疗效与安全性——一项双盲、多中心、随机、安慰剂对照的剂量反应研究。
Cephalalgia. 2002 Sep;22(7):523-32. doi: 10.1046/j.1468-2982.2002.00396.x.
10
Intravenous magnesium sulphate in the acute treatment of migraine without aura and migraine with aura. A randomized, double-blind, placebo-controlled study.静脉注射硫酸镁用于无先兆偏头痛和有先兆偏头痛的急性治疗。一项随机、双盲、安慰剂对照研究。
Cephalalgia. 2002 Jun;22(5):345-53. doi: 10.1046/j.1468-2982.2002.00364.x.