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营养保健品在儿童和青少年头痛治疗中的应用。

The use of nutraceutics in children's and adolescent's headache.

作者信息

Sangermani R, Boncimino A

机构信息

Neurology Department, S.Carlo Borromeo Hospital, Milan, Italy.

Local health authority, Lodi, Italy.

出版信息

Neurol Sci. 2017 May;38(Suppl 1):121-124. doi: 10.1007/s10072-017-2896-7.

DOI:10.1007/s10072-017-2896-7
PMID:28527085
Abstract

Nutraceutics are the most used non-pharmacological remedies for migraine's prophylaxis in children and adolescents. Doctors interested in use of nutraceuticals for a complete treatment of children's headache should be adequately informed on this treatments' efficacy and safety. Actually there is a lack of official guidelines about use of nutraceuticals in migraine's prevention in children and adolescent and there are few studies with limited efficacy evidences. The most used nutraceuticals for adolescent's and children's headache prophylaxis are: magnesium, coenzyme Q10, riboflavin, butterbur, feverfew and melatonin. Further Randomised Controlled Trials are needed for a better effectiveness evaluation in nutraceuticals' use for migraine treatment in child and adolescent.

摘要

营养疗法是儿童和青少年偏头痛预防中最常用的非药物疗法。对使用营养疗法全面治疗儿童头痛感兴趣的医生应充分了解这种疗法的疗效和安全性。实际上,目前缺乏关于营养疗法在儿童和青少年偏头痛预防中应用的官方指南,且仅有少数研究,其疗效证据有限。用于青少年和儿童头痛预防的最常用营养疗法有:镁、辅酶Q10、核黄素、小白菊、菊叶香藜和褪黑素。需要进一步进行随机对照试验,以便更好地评估营养疗法在儿童和青少年偏头痛治疗中的有效性。

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Semin Pediatr Neurol. 2016 Feb;23(1):44-52. doi: 10.1016/j.spen.2016.01.010. Epub 2016 Jan 30.
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Nutraceuticals in Acute and Prophylactic Treatment of Migraine.营养保健品在偏头痛的急性和预防性治疗中的应用
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水提取物的抗炎和神经调节作用:来自计算机模拟、体外和离体研究的结果。
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Efficacy of Topiramate Alone and Topiramate Plus Vitamin D3 in the Prophylaxis of Pediatric Migraine: A Randomized Clinical Trial.托吡酯单药及托吡酯联合维生素D3预防儿童偏头痛的疗效:一项随机临床试验
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An observational study of fixed-dose Tanacetum parthenium nutraceutical preparation for prophylaxis of pediatric headache.一项固定剂量菊蒿营养补充剂预防儿童头痛的观察性研究。
Ital J Pediatr. 2019 Mar 12;45(1):36. doi: 10.1186/s13052-019-0624-z.
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Non-pharmacological Approaches for Headaches in Young Age: An Updated Review.青少年头痛的非药物治疗方法:最新综述
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Non-Rapid Eye Movement Sleep Parasomnias and Migraine: A Role of Orexinergic Projections.非快速眼动睡眠异态睡眠与偏头痛:食欲素能投射的作用
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News on the journal Neurological Sciences in 2017.2017年《神经科学杂志》上的新闻。
Neurol Sci. 2018 Jan;39(1):15-21. doi: 10.1007/s10072-017-3241-x.
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Preventive drugs in childhood and adolescent migraine.儿童和青少年偏头痛的预防性药物
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Cephalalgia. 2014 Jul;34(8):568-83. doi: 10.1177/0333102413519512. Epub 2014 Jan 17.
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Complementary and alternative medicine in children: an analysis of the recent literature.儿童补充和替代医学:对近期文献的分析。
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Nutraceutical preparations in childhood migraine prophylaxis: effects on headache outcomes including disability and behaviour.儿童偏头痛预防中的营养保健品:对头痛结局(包括残疾和行为)的影响。
Neurol Sci. 2012 Dec;33(6):1365-8. doi: 10.1007/s10072-012-1019-8. Epub 2012 Mar 23.
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High-dose riboflavin for migraine prophylaxis in children: a double-blind, randomized, placebo-controlled trial.高剂量核黄素用于儿童偏头痛预防:一项双盲、随机、安慰剂对照试验。
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