Medizinische Universitätsklinik, Abteilung Rehabilitative und Präventive Sportmedizin, Freiburg, Germany.
J Sci Med Sport. 2009 Nov;12(6):673-5. doi: 10.1016/j.jsams.2008.06.005. Epub 2008 Sep 2.
The underlying mechanisms of altitude training are still a matter of controversial discussion but erythropoietic adaptations with an increase of total haemoglobin mass (tHb) have been shown in several studies, partly depending on an adequate hypoxic dose. The aim of this retrospective study was to investigate if a 3 weeks sojourn at moderate altitude (1816 m) with conventional training sessions (live and train at moderate altitude), especially under real and uncontrolled conditions, results in an increased tHb. tHb was measured in seven male cyclists competing at elite level (German national cycling team, U23 category) prior to the ascent to altitude and immediately after descent to sea-level. The athletes completed a 21 days altitude training camp living at 1816 m and training at 1800-2400 m during the competitive season. No significant difference was found in tHb after the altitude sojourn (prior 927+/-109g vs. 951+/-113g post, 95% CI -13-61g). Additionally, the analysis of red cell volume, plasma volume and blood volume or haemoglobin concentration [Hb] as well as haematocrit (Hct) did not reveal any significant changes. The data supports the theory that an adequate hypoxic dose is required for adaptations of the erythropoietic system with an increase of tHb and a threshold of approximately 2100-2500 m has to be exceeded.
高原训练的潜在机制仍然存在争议，但已有多项研究表明，高原训练会引起红细胞生成适应性变化，总血红蛋白量（tHb）增加，这部分取决于适当的低氧剂量。本回顾性研究的目的是探讨在中等海拔高度（1816 米）进行为期 3 周的逗留，同时进行常规训练（在中等海拔高度生活和训练），特别是在真实和不受控制的条件下，是否会导致 tHb 增加。在海拔升高前和海拔下降后，7 名参加精英级别的男性自行车运动员（德国国家自行车队，U23 组）测量 tHb。运动员在比赛季节期间居住在 1816 米处，并在 1800-2400 米处进行 21 天的高原训练。高原逗留后 tHb 没有明显差异（之前 927+/-109g 与之后 951+/-113g，95%置信区间 -13-61g）。此外，红细胞体积、血浆体积和血容量或血红蛋白浓度[Hb]以及红细胞压积（Hct）的分析也没有显示出任何显著变化。数据支持这样一种理论，即需要适当的低氧剂量才能使红细胞生成系统适应，tHb 增加，并且必须超过大约 2100-2500 米的阈值。
