Lloyd Jacqueline J, Strathdee Steffanie A, Pu Minya, Havens Jennifer R, Cornelius Llewellyn J, Huettner Steven, Latkin Carl A
Temple University School of Social Administration, Philadelphia, Pennsylvania, USA.
Am J Addict. 2008 Sep-Oct;17(5):414-21. doi: 10.1080/10550490802268165.
This study examined whether participation in opiate drug treatment is associated with changes in drug use and injecting drug use within the social networks of injecting drug users. Participants were 245 injecting drug users who attended the Baltimore Needle Exchange Program during 2002-2004 and requested treatment and received a referral for opiate agonist treatment as part of an intervention to improve treatment outcomes. Data included interviews at baseline, 3, 6, 12, and 18 months and drug treatment program agency records. The mean age of participants was 42.2 years; 77% were African American, 69% were male, and 48% entered treatment. Final generalized estimating equations (GEE) models indicated that participants that entered opiate drug treatment exhibited approximately a 20% decrease in the proportional odds of having friends that used drugs (p = 0.04). Additionally, participants that entered opiate drug treatment exhibited a 26% decrease in the proportional odds of having friends that injected drugs (p = 0.01). These findings contribute evidence to further understand the dynamics between opiate drug treatment, changes in social network risk, and treatment outcomes, as well as suggest an important role for peer-based interventions to support entry and retention in opiate drug treatment.
本研究探讨了参与阿片类药物治疗是否与注射吸毒者社交网络内的药物使用及注射吸毒行为的变化相关。研究对象为245名在2002年至2004年期间参加巴尔的摩针头交换项目并寻求治疗的注射吸毒者，他们作为改善治疗效果干预措施的一部分，被转介接受阿片类激动剂治疗。数据包括在基线、3个月、6个月、12个月和18个月时的访谈以及药物治疗项目机构记录。参与者的平均年龄为42.2岁；77%为非裔美国人，69%为男性，48%接受了治疗。最终的广义估计方程（GEE）模型表明，接受阿片类药物治疗的参与者拥有吸毒朋友的比例概率下降了约20%（p = 0.04）。此外，接受阿片类药物治疗的参与者拥有注射吸毒朋友的比例概率下降了26%（p = 0.01）。这些研究结果为进一步理解阿片类药物治疗、社交网络风险变化和治疗效果之间的动态关系提供了证据，同时也表明基于同伴的干预措施在支持阿片类药物治疗的进入和维持方面具有重要作用。
