Georges C G, Artunc F, Weyrich P, Friedrich B, Wolf S C
Medizinische Universitätsklinik, Abteilung IV, Sektion für Nieren und Hochdruckkrankheiten, Tübingen.
Dtsch Med Wochenschr. 2008 Sep;133(37):1830-2. doi: 10.1055/s-0028-1082803. Epub 2008 Sep 3.
A 29-year-old woman in the early stage of pregnancy ( approximately 6 (th) week) presented in our hospital with influenza-like symptoms of fever, headache, aching limbs and tenderness over the costovertebral angle. Acute oliguric renal failure occurred within a few days.
Ultrasonography revealed symmetrically enlarged kidneys with a small amount of perirenal fluids. The blood count showed thrombocytopenia, and viral serology verified a recent infection with Puumala virus (species of Hantavirus).
Epidemic nephropathy was diagnosed. The patient underwent one session of hemodialysis and soon recovered without any residual renal damage. The pregnancy continued without any further complications.
There are only few reports on infections with Puumala virus during pregnancy are. None of theses described any fetal abnormalities causes by the maternal infection, as in our patient. Hantavirus infections should be considered in differential diagnosis of acute renal failure in endemic regions.
一名29岁处于妊娠早期（约第6周）的女性因发热、头痛、四肢酸痛及肋脊角压痛等流感样症状前来我院就诊。数天内出现急性少尿性肾衰竭。
超声检查显示双肾对称肿大，肾周有少量积液。血常规显示血小板减少，病毒血清学证实近期感染普马拉病毒（汉坦病毒属）。
诊断为流行性肾病。患者接受了一次血液透析，很快康复，无任何残余肾损伤。妊娠继续，无任何进一步并发症。
关于妊娠期感染普马拉病毒的报道很少。这些报道均未描述如我们患者中母体感染导致的任何胎儿异常情况。在流行地区，急性肾衰竭的鉴别诊断中应考虑汉坦病毒感染。
