Kim H I, Kim D H, Yoon M S, Kim H J, Lee S
Department of Microbiology, Ajou University College of Medicine, Suwon, Korea.
Yonsei Med J. 1991 Mar;32(1):79-81. doi: 10.3349/ymj.1991.32.1.79.
The authors reviewed two patients showing "vitiligo-like depigmentations" where the skin had been in close contact with a metal spectacle frame made of nickel alloy. In spite of the hypersensitivity to nickel in both patients, they showed clinical and histologic findings indicate that the formation of "vitiligo-like depigmentation" does not result from posinflammatory hypopigmentation but from chemical hypomelanosis. We could not explain the underlying mechanisms; however, the speculation that the "vitiligo-like depigmentation" may come from the direct effect of the nickel itself, prompted us to report these cases.
作者回顾了两名出现“白癜风样色素脱失”的患者，他们的皮肤曾与镍合金制成的金属眼镜架密切接触。尽管两名患者对镍均过敏，但临床和组织学检查结果表明，“白癜风样色素脱失”的形成并非源于炎症后色素减退，而是化学性黑素减少。我们无法解释其潜在机制；然而，“白癜风样色素脱失”可能源于镍本身的直接作用这一推测促使我们报告这些病例。
