Rohart C, Fajnkuchen F, Nghiem-Buffet S, Abitbol O, Badelon I, Chaine G
Service d'ophtalmologie, Hôpital Avicenne, Université Paris XIII, Bobigny, France.
J Fr Ophtalmol. 2008 Jun;31(6 Pt 1):571-7. doi: 10.1016/s0181-5512(08)75457-3.
To assess the benefits of cataract surgery in patients with age-related macular degeneration (AMD) in terms of visual acuity and quality of life.
Forty-two eyes of 30 patients were included in this prospective study between October 2003 and January 2005. The eyes were divided into two groups: the first group (n=12) with geographic atrophy and neovascularization (late-stage AMD) and the second group (n=30) with drusen and retinal pigment epithelium abnormalities (early-stage AMD). Assessment included best corrected visual acuity (BCVA) and quality-of-life measures (VF-14 questionnaire) before surgery and BCVA and the VF-14 score after surgery.
In the first group, there was no statistical difference but a trend toward improvement in BCVA (p>0.05). In terms of quality of life, there was a statistical difference between pre- and postoperative VF-14 (p=0.0078). In the second group, there was a statistical difference between pre- and postoperative BVCA (p<0.0001). In terms of quality of life, there was a statistical difference between pre- and postoperative VF-14 (p<0.0001).
This study shows a benefit in terms of visual acuity and quality of life in the majority of patients with age-related maculopathy after cataract surgery, even in late-stage AMD. Indeed, we noted a marked improvement in visual acuity in cases of early-stage AMD and a slight improvement of visual acuity in late-stage AMD. Quality of life was improved at both stages. In conclusion, cataract surgery is justified in patients with AMD.
评估年龄相关性黄斑变性(AMD)患者白内障手术在视力和生活质量方面的益处。
2003年10月至2005年1月期间,30例患者的42只眼纳入本前瞻性研究。将这些眼分为两组:第一组(n = 12)为地图样萎缩和新生血管形成(晚期AMD),第二组(n = 30)为玻璃膜疣和视网膜色素上皮异常(早期AMD)。评估包括手术前的最佳矫正视力(BCVA)和生活质量指标(VF - 14问卷)以及手术后的BCVA和VF - 14评分。
在第一组中,BCVA虽无统计学差异,但有改善趋势(p>0.05)。在生活质量方面,术前和术后VF - 14有统计学差异(p = 0.0078)。在第二组中,术前和术后BVCA有统计学差异(p<0.0001)。在生活质量方面,术前和术后VF - 14有统计学差异(p<0.0001)。
本研究表明,大多数年龄相关性黄斑病变患者白内障手术后在视力和生活质量方面有益,即使是晚期AMD患者。实际上,我们注意到早期AMD患者视力有显著改善,晚期AMD患者视力有轻微改善。两个阶段的生活质量均有所提高。总之,AMD患者进行白内障手术是合理的。