Narayan Sanjiv M
University of California and VA Medical Center, La Jolla, CA, USA.
Prog Cardiovasc Dis. 2008 Sep-Oct;51(2):118-27. doi: 10.1016/j.pcad.2007.11.001.
T-wave alterans (TWA) measures alternate-beat fluctuations in the ECG T-wave, and has been used to predict the risk for life-threatening ventricular arrhythmias in various clinical populations. This work reviews the traditional literature linking repolarization alternans in cellular and tissue-level studies, with clinical studies that TWA can successfully add to existing clinical risk factors in predicting ventricular arrhythmias. We conclude by providing an evidence-based framework integrating TWA with other risk factors to stratify risk for sudden cardiac arrest.
T波交替(TWA)测量心电图T波中的逐搏波动,并已用于预测各种临床人群中危及生命的室性心律失常风险。这项工作回顾了在细胞和组织水平研究中连接复极交替的传统文献,以及TWA能够成功地在预测室性心律失常时增加现有临床风险因素的临床研究。我们通过提供一个基于证据的框架来总结,该框架将TWA与其他风险因素整合起来,以对心脏骤停风险进行分层。