卵裂球活检对植入前小鼠胚胎发育及整体基因表达的影响。
The effect of blastomere biopsy on preimplantation mouse embryo development and global gene expression.
作者信息
Duncan Francesca E, Stein Paula, Williams Carmen J, Schultz Richard M
机构信息
Center for Research on Reproduction and Women's Health, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.
出版信息
Fertil Steril. 2009 Apr;91(4 Suppl):1462-5. doi: 10.1016/j.fertnstert.2008.07.1710. Epub 2008 Sep 6.
Abstract
The blastomere biopsy procedure does not affect preimplantation embryo development or global patterns of gene expression in a mouse model of Preimplantation Genetic Testing (PGT). However, zona breaching, which is inherent to the blastomere biopsy procedure, causes significant premature and sometimes abnormal hatching.
摘要
在胚胎植入前遗传学检测（PGT）小鼠模型中，卵裂球活检程序不会影响植入前胚胎发育或基因表达的整体模式。然而，卵裂球活检程序所固有的透明带破裂会导致显著的过早孵化，有时还会出现异常孵化。
相似文献
1
The effect of blastomere biopsy on preimplantation mouse embryo development and global gene expression.卵裂球活检对植入前小鼠胚胎发育及整体基因表达的影响。
Fertil Steril. 2009 Apr;91(4 Suppl):1462-5. doi: 10.1016/j.fertnstert.2008.07.1710. Epub 2008 Sep 6.
2
Different embryonic development after blastomere biopsy for preimplantation genetic diagnosis, observed by time-lapse imaging.通过延时成像观察，卵裂球活检用于植入前基因诊断后的不同胚胎发育情况。
Fertil Steril. 2009 Oct;92(4):1470-1471. doi: 10.1016/j.fertnstert.2009.03.009. Epub 2009 Apr 9.
3
Pregnancy outcome in preimplantation genetic diagnosis cycle by blastomere biopsy is related to both quality and quantity of embryos on day 3.通过卵裂球活检进行植入前基因诊断周期的妊娠结局与第3天胚胎的质量和数量均相关。
Fertil Steril. 2009 Apr;91(4 Suppl):1355-7. doi: 10.1016/j.fertnstert.2008.03.054.
4
Optimal timing for blastomere biopsy of 8-cell embryos for preimplantation genetic diagnosis.8 细胞胚胎卵裂球活检用于植入前遗传学诊断的最佳时机。
Hum Reprod. 2018 Jan 1;33(1):32-38. doi: 10.1093/humrep/dex343.
5
Preimplantation genetic diagnosis for chromosome rearrangements - one blastomere biopsy versus two blastomere biopsy.胚胎植入前遗传学诊断用于染色体结构重排：卵裂球活检 1 个与卵裂球活检 2 个的比较。
J Assist Reprod Genet. 2012 Aug;29(8):821-7. doi: 10.1007/s10815-012-9782-2. Epub 2012 May 12.
6
Human embryonic development after blastomere removal: a time-lapse analysis.卵裂球去除后人类胚胎的发育：延时分析。
Hum Reprod. 2012 Jan;27(1):97-105. doi: 10.1093/humrep/der382. Epub 2011 Nov 10.
7
Blastomere biopsy for PGD delays embryo compaction and blastulation: a time-lapse microscopic analysis.用于胚胎植入前基因诊断的卵裂球活检会延迟胚胎致密化和囊胚形成：一项延时显微镜分析。
J Assist Reprod Genet. 2016 Nov;33(11):1449-1457. doi: 10.1007/s10815-016-0813-2. Epub 2016 Oct 1.
8
Aberrant behavior of mouse embryo development after blastomere biopsy as observed through time-lapse cinematography.通过延时摄影观察到的胚胎细胞活检后小鼠胚胎发育的异常行为。
Fertil Steril. 2010 May 15;93(8):2723-8. doi: 10.1016/j.fertnstert.2009.06.056. Epub 2009 Aug 8.
9
Timing day-3 vitrification for PGT-M embryos: pre- or post-blastomere biopsy?PGT-M 胚胎第 3 天玻璃化：卵裂球活检前还是活检后？
J Assist Reprod Genet. 2020 Oct;37(10):2413-2418. doi: 10.1007/s10815-020-01914-3. Epub 2020 Aug 8.
10
Does sperm DNA fragmentation affect the developmental potential and the incidence of apoptosis following blastomere biopsy?精子DNA碎片化是否会影响卵裂球活检后的发育潜能及细胞凋亡发生率？
Syst Biol Reprod Med. 2016;62(1):1-10. doi: 10.3109/19396368.2015.1103324. Epub 2015 Dec 17.
引用本文的文献
1
Blastomere biopsy for PGD delays embryo compaction and blastulation: a time-lapse microscopic analysis.用于胚胎植入前基因诊断的卵裂球活检会延迟胚胎致密化和囊胚形成：一项延时显微镜分析。
J Assist Reprod Genet. 2016 Nov;33(11):1449-1457. doi: 10.1007/s10815-016-0813-2. Epub 2016 Oct 1.
2
The Impact of Biopsy on Human Embryo Developmental Potential during Preimplantation Genetic Diagnosis.活检对植入前基因诊断期间人类胚胎发育潜能的影响。
Biomed Res Int. 2016;2016:7193075. doi: 10.1155/2016/7193075. Epub 2016 Jan 28.
3
In vitro fertilization (IVF) in mammals: epigenetic and developmental alterations. Scientific and bioethical implications for IVF in humans.哺乳动物的体外受精（IVF）：表观遗传和发育改变。对人类体外受精的科学和生物伦理影响。
Biol Res. 2015 Dec 18;48:68. doi: 10.1186/s40659-015-0059-y.
4
Aneuploidy analysis of non-pronuclear embryos from IVF with use of array CGH: a case report.使用阵列比较基因组杂交技术对体外受精获得的无原核胚胎进行非整倍体分析：一例报告
J Mol Histol. 2014 Jun;45(3):269-74. doi: 10.1007/s10735-013-9556-x. Epub 2013 Dec 1.
5
Rho-associated kinase activity is required for proper morphogenesis of the inner cell mass in the mouse blastocyst.Rho 相关激酶活性对于小鼠囊胚内细胞团的正常形态发生是必需的。
Biol Reprod. 2013 Nov 21;89(5):122. doi: 10.1095/biolreprod.113.109470. Print 2013 Nov.
6
Biopsy of embryos produced by in vitro fertilization affects development in C57BL/6 mouse strain.体外受精产生的胚胎活检会影响 C57BL/6 品系小鼠的发育。
Theriogenology. 2013 Jan 15;79(2):234-41. doi: 10.1016/j.theriogenology.2012.08.007. Epub 2012 Nov 19.
7
Blastomere removal from cleavage-stage mouse embryos alters steroid metabolism during pregnancy.从卵裂期的小鼠胚胎中去除卵裂球会改变妊娠期间的类固醇代谢。
Biol Reprod. 2012 Jul 5;87(1):4, 1-9. doi: 10.1095/biolreprod.111.097444. Print 2012 Jul.
8
Mouse females devoid of exposure to males during fetal development exhibit increased maternal behavior.在胎儿发育过程中，没有接触雄性的雌性老鼠表现出更多的母性行为。
Psychoneuroendocrinology. 2012 Mar;37(3):383-95. doi: 10.1016/j.psyneuen.2011.07.009. Epub 2011 Jul 30.
本文引用的文献
1
Dichorionic triamniotic triplet pregnancy with monozygotic twins discordant for trisomy 13 after preimplantation genetic screening: case report.植入前基因筛查后出现的双绒毛膜三羊膜囊三胎妊娠，其中单卵双胎之一为13三体，另一个正常：病例报告
Fertil Steril. 2008 Nov;90(5):2017.e5-9. doi: 10.1016/j.fertnstert.2008.01.095. Epub 2008 Apr 9.
2
Preimplantation genetic testing: a Practice Committee opinion.植入前基因检测：实践委员会意见
Fertil Steril. 2007 Dec;88(6):1497-504. doi: 10.1016/j.fertnstert.2007.10.010. Epub 2007 Oct 17.
3
Effect of in vitro fertilization on gene expression and development of mouse preimplantation embryos.体外受精对小鼠植入前胚胎基因表达和发育的影响。
Reproduction. 2007 Jul;134(1):63-72. doi: 10.1530/REP-06-0247.
4
Removal of 2 cells from cleavage stage embryos is likely to reduce the efficacy of chromosomal tests that are used to enhance implantation rates.从卵裂期胚胎中移除2个细胞可能会降低用于提高着床率的染色体检测的效能。
Fertil Steril. 2007 Mar;87(3):496-503. doi: 10.1016/j.fertnstert.2006.07.1516. Epub 2006 Dec 4.
5
Is there increased monozygotic twinning after assisted reproductive technology?辅助生殖技术后单卵双胎发生率会增加吗？
Aust N Z J Obstet Gynaecol. 2005 Oct;45(5):360-4. doi: 10.1111/j.1479-828X.2005.00451.x.
6
Transcript profiling during mouse oocyte development and the effect of gonadotropin priming and development in vitro.小鼠卵母细胞发育过程中的转录谱分析以及促性腺激素预处理和体外发育的影响
Dev Biol. 2005 Oct 15;286(2):493-506. doi: 10.1016/j.ydbio.2005.08.023. Epub 2005 Oct 5.
7
Effects of embryo culture on global pattern of gene expression in preimplantation mouse embryos.胚胎培养对植入前小鼠胚胎基因表达整体模式的影响。
Reproduction. 2004 Sep;128(3):301-11. doi: 10.1530/rep.1.00297.
8
Over a decade of experience with preimplantation genetic diagnosis.十多年的胚胎植入前基因诊断经验。
Fertil Steril. 2004 Aug;82(2):302-3. doi: 10.1016/j.fertnstert.2004.02.108.
9
Transcript profiling during preimplantation mouse development.小鼠植入前发育过程中的转录本分析。
Dev Biol. 2004 Aug 15;272(2):483-96. doi: 10.1016/j.ydbio.2004.05.018.
10
Visualization of atypical hatching of a human blastocyst in vitro forming two identical embryos.体外观察到人类囊胚异常孵化形成两个相同胚胎的过程。
Fertil Steril. 2003 Dec;80(6):1502-3. doi: 10.1016/j.fertnstert.2003.07.001.
Zotero 插件