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Greener biocatalytic approach to the synthesis of nucleosides and their precursors.

作者信息

Singh Sunil K, Sharma Raman K, Maity Jyotirmoy, Wengel Jesper, Parmar Virinder S, Prasad Ashok K

机构信息

Bioorganic Laboratory, Department of Chemistry, University of Delhi, Delhi-110 007, India.

出版信息

Nucleic Acids Symp Ser (Oxf). 2008(52):273-4. doi: 10.1093/nass/nrn138.

DOI:10.1093/nass/nrn138
PMID:18776359
Abstract

Novel, efficient and selective biocatalytic acylation / deacylation strategies have been used for the greener synthesis of precursors of different bicyclonucleosides. Biocatalytic methodology has also been developed for the separation of pyrano- and furanonucleosides, which is otherwise almost impossible to achieve by usual chemical approach.

摘要

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