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用于乳腺肿瘤发生的瑞士白化小鼠种群的双向选择:两种新菌株(SHN和SLN)的建立。

Two-way selection of a stock of Swiss albino mice for mammary tumorigenesis: establishment of two new strains (SHN and SLN).

作者信息

Nagasawa H, Yanai R, Taniguchi H, Tokuzen R, Nakahara W

出版信息

J Natl Cancer Inst. 1976 Aug;57(2):425-30. doi: 10.1093/jnci/57.2.425.

Abstract

Two mouse strains (SHN and SLN) with high and low incidences, respectively, of mammary tumors were established from the same basal stock of Swiss albino mice that were unrelated in origin to other mouse strains with mammary tumors. In the breeders, mammary tumor incidence and average age of the mice when they developed mammary tumors were 97.2 % and 6.6 months for SHN, and 5.57% and 10.1 months for SLN, respectively...

摘要

分别从瑞士白化小鼠的同一基础种群培育出两种乳腺肿瘤发病率高低不同的小鼠品系(SHN和SLN),该基础种群在起源上与其他乳腺肿瘤小鼠品系无关。在种鼠中,SHN的乳腺肿瘤发病率及发生乳腺肿瘤时小鼠的平均年龄分别为97.2%和6.6个月,SLN则分别为5.57%和10.1个月……

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