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日本培育的欧洲起源近交系小鼠品系中的乳腺肿瘤病毒抗原表达。

Mammary tumor virus antigen expression in inbred mouse strains of European origin established in Japan.

作者信息

Imai S, Morimoto J, Tsubura Y, Hilgers J

出版信息

Gan. 1980 Aug;71(4):419-24.

PMID:6253345
Abstract

Expression of the mammary tumor virus (MTV) antigen in the milk from inbred mouse strains maintained in Japanese laboratories was investigated by means of the immunodiffusion test (ID) and the results were compared with the incidence of mammary tumors in breeding females of identical strains. Japanese strains tested were classified into two groups. The DD/Tbr, DDD and KF strains were derived from "dd" stock mice, and they showed equally high incidences of MTV antigen expression in the milk, though each strain developed mammary tumors with different incidences; 71%, 14% and 22%, respectively. Other strains originated from Swiss albino mice. The incidence of MTV antigen expression in the milk of SHN and SLN strains was the same as that of mammary tumors at an early age.

摘要

通过免疫扩散试验(ID)研究了日本实验室饲养的近交系小鼠乳汁中乳腺肿瘤病毒(MTV)抗原的表达情况,并将结果与相同品系繁殖雌鼠的乳腺肿瘤发病率进行了比较。所检测的日本品系分为两组。DD/Tbr、DDD和KF品系源自“dd”原种小鼠,它们乳汁中MTV抗原表达的发生率同样很高,尽管各品系乳腺肿瘤的发生率不同,分别为71%、14%和22%。其他品系源自瑞士白化小鼠。SHN和SLN品系乳汁中MTV抗原表达的发生率与幼年时乳腺肿瘤的发生率相同。

相似文献

1
Mammary tumor virus antigen expression in inbred mouse strains of European origin established in Japan.日本培育的欧洲起源近交系小鼠品系中的乳腺肿瘤病毒抗原表达。
Gan. 1980 Aug;71(4):419-24.
2
Strain difference in the expression of mammary tumor virus antigen in the male genital organs of mice during aging.衰老过程中小鼠雄性生殖器官中乳腺肿瘤病毒抗原表达的品系差异。
Gan. 1981 Jun;72(3):424-9.
3
A new locus (Mtv-4) for endogenous mammary tumor virus expression and early mammary tumor development in the SHN mouse strain.SHN小鼠品系中内源性乳腺肿瘤病毒表达和早期乳腺肿瘤发生的一个新基因座(Mtv-4)。
J Natl Cancer Inst. 1983 Sep;71(3):517-21.
4
MuMTV antigen expression and mammary tumor incidence in non-inbred dd mice.非近交系dd小鼠中多瘤病毒(MuMTV)抗原表达与乳腺肿瘤发生率
Jikken Dobutsu. 1982 Apr;31(2):107-11. doi: 10.1538/expanim1978.31.2_107.
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Genetic transmission of mammary tumour virus by GR mice.GR小鼠对乳腺肿瘤病毒的遗传传递。
Int J Cancer. 1977 Mar 15;19(3):383-90. doi: 10.1002/ijc.2910190316.
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Inability to predict mammary tumorigenesis in strain A mice from presence of mammary tumor virus or antigen in the milk.无法根据A品系小鼠乳汁中乳腺肿瘤病毒或抗原的存在情况来预测乳腺肿瘤发生。
J Natl Cancer Inst. 1970 Nov;45(5):937-40.
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Tissue and organ distribution of mammary tumor virus antigens in low and high mammary cancer strain mice.乳腺肿瘤病毒抗原在低发和高发乳腺癌品系小鼠中的组织和器官分布
Eur J Cancer Clin Oncol. 1983 Jul;19(7):1011-9. doi: 10.1016/0277-5379(83)90071-8.
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Establishment of DDD/1-Mtv-2/Mtv-2, nu/nu and DDD/1-Mtv-2/Mtv-2, nu/+ mice: preliminary characterization in relation to MTV antigen expression and mammary tumorigenesis.DDD/1-Mtv-2/Mtv-2、裸鼠(nu/nu)以及DDD/1-Mtv-2/Mtv-2、杂合裸鼠(nu/+)的建立:与MTV抗原表达及乳腺肿瘤发生相关的初步特征分析
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Immunologic, virologic, and genetic aspects of mammary tumor virus-induced cell-surface antigens: presence of these antigens and the Thy 1.2 antigen on murine mammary gland and tumor cells.乳腺肿瘤病毒诱导的细胞表面抗原的免疫学、病毒学和遗传学方面:这些抗原及Thy 1.2抗原在小鼠乳腺和肿瘤细胞上的存在情况。
J Natl Cancer Inst. 1975 Jun;54(6):1323-33. doi: 10.1093/jnci/54.6.1323.
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Development of a congeneic line of the GR mouse strain without early mammary tumours.培育无早期乳腺肿瘤的GR小鼠品系的同源近交系。
Int J Cancer. 1977 Oct 15;20(4):588-94. doi: 10.1002/ijc.2910200417.

引用本文的文献

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Mouse Mammary Tumor Virus Proviral Integration in the DD/Tbr Mice.小鼠乳腺肿瘤病毒前病毒在DD/Tbr小鼠中的整合
Breast Cancer. 1994 Jul 30;1(1):11-16. doi: 10.1007/BF02967369.