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土耳其脑膜脑炎:感染的致病和免疫学方面

Turkey meningo-encephalitis: pathogenic and immunological aspects of the infection.

作者信息

Ianconescu M, Aharonovici A, Samberg Y, Hornstein K, Merdinger M

机构信息

Kimron Veterinary Institute, Tel Aviv University, Israel.

出版信息

Avian Pathol. 1973 Oct;2(4):251-62. doi: 10.1080/03079457309353801.

DOI:10.1080/03079457309353801
PMID:18777402
Abstract

The distribution of turkey meningo-encephalitis virus in infected birds and the development of immunity were studied. The turkey meningo-encephalitis virus was present in the blood as early as 24 h after experimental inoculation, and persisted for 5-8 d. Antibodies could be detected about the 5th d. A good correlation was found between haemagglutinin-inhibiting and virus-neutralizing antibodies. The virus could not be reisolated from any blood or organ sample collected after the 14th d and no sign of latent infection or carrier state could be found. The infection did not spread from the inoculated turkeys to control un inoculated birds in close contact. The possible existence of a natural reservoir and an arthropod vector of this virus is discussed.

摘要

对火鸡脑膜脑炎病毒在感染禽类中的分布及免疫发展情况进行了研究。早在实验接种后24小时,火鸡脑膜脑炎病毒就出现在血液中,并持续存在5 - 8天。大约在第5天可检测到抗体。血凝抑制抗体和病毒中和抗体之间存在良好的相关性。在第14天后采集的任何血液或器官样本中均未重新分离到该病毒,也未发现潜伏感染或携带状态的迹象。感染并未从接种的火鸡传播到密切接触的未接种对照禽类。讨论了该病毒天然宿主和节肢动物传播媒介可能存在的情况。

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