Balderson S Scott, D'Amico Thomas A
Department of Surgery, Duke University Medical Center, Box 3496, Durham, NC 27710, USA.
Curr Oncol Rep. 2008 Jul;10(4):283-6. doi: 10.1007/s11912-008-0044-5.
Surgical resection is the primary treatment for early-stage non-small cell lung cancer (NSCLC). While open thoracotomy is the most frequently performed approach for lobectomy, minimally invasive surgical resection is a safe and viable alternative. Thoracoscopic lobectomy, also termed video-assisted thoracoscopic surgery lobectomy, is defined as the anatomic resection of an entire lobe of the lung-including mediastinal lymph node dissection-using a thoracoscope and an access incision without using a mechanical retractor and spreading of the ribs. As the procedure has evolved and been studied, thoracoscopic lobectomy has been demonstrated to be a safe and oncologically effective strategy in the surgical management of patients with stage I or II NSCLC, as well as selected patients with stage III NSCLC after induction therapy. Advantages of this approach include less postoperative pain, shorter chest tube duration and subsequent length of stay, fewer overall complications, better compliance with adjuvant chemotherapy, faster return to full activity, and greater preservation of pulmonary function.
手术切除是早期非小细胞肺癌（NSCLC）的主要治疗方法。虽然开胸手术是肺叶切除术最常用的方法，但微创外科手术切除是一种安全可行的替代方法。电视辅助胸腔镜手术肺叶切除术，也称为胸腔镜肺叶切除术，定义为使用胸腔镜和一个切口，在不使用机械牵开器和不撑开肋骨的情况下，对整个肺叶进行解剖性切除，包括纵隔淋巴结清扫。随着该手术方法的不断发展和研究，胸腔镜肺叶切除术已被证明是治疗I期或II期NSCLC患者以及诱导治疗后部分III期NSCLC患者的一种安全且具有肿瘤学疗效的手术策略。这种方法的优点包括术后疼痛减轻、胸管留置时间和随后的住院时间缩短、总体并发症减少、辅助化疗的依从性更好、更快恢复完全活动以及更好地保留肺功能。
