Harvey Andrea M, Hibbert Angie, Barrett Esther L, Day Michael J, Quiggin Anna V, Brannan Rachael M, Caney Sarah M A
Department of Clinical Veterinary Science, Division of Companion Animals, University of Bristol, Langford, Bristol BS40 5DU, United Kingdom.
J Feline Med Surg. 2009 Feb;11(2):96-106. doi: 10.1016/j.jfms.2008.05.007. Epub 2008 Sep 10.
The aim of this study was to characterise the scintigraphic findings in a large population of hyperthyroid cats in order to determine the location of thyroid pathology in newly diagnosed hyperthyroid cats and those that had previously undergone thyroidectomy. A specific aim was to identify the proportion of cats with ectopic hyperfunctional thyroid tissue and characterise the scintigraphic and clinical features of this subset of cats. Nearly one in five hyperthyroid cats was identified to have multiple areas of hyperfunctional thyroid tissue and/or intrathoracic hyperfunctional thyroid tissue where surgical thyroidectomy would not be curative. In addition, this study demonstrated that scintigraphy cannot reliably distinguish between thyroid carcinoma and adenoma. Owners should always be warned about the possibility of ectopic thyroid tissue before thyroidectomy is performed. In this study, intrathoracic hyperfunctional thyroid tissue and multiple areas of increased radionuclide uptake (IRU) were a common feature of benign thyroid disease and responded well to treatment with low dose radioiodine.
本研究的目的是对大量甲状腺功能亢进猫的闪烁扫描结果进行特征描述,以确定新诊断的甲状腺功能亢进猫及先前接受过甲状腺切除术的猫的甲状腺病变位置。一个特定目标是确定具有异位高功能甲状腺组织的猫的比例,并描述这一亚组猫的闪烁扫描和临床特征。近五分之一的甲状腺功能亢进猫被发现有多个高功能甲状腺组织区域和/或胸腔内高功能甲状腺组织,而手术甲状腺切除术对此无法治愈。此外,本研究表明闪烁扫描无法可靠地区分甲状腺癌和腺瘤。在进行甲状腺切除术之前,应始终告知猫主人存在异位甲状腺组织的可能性。在本研究中,胸腔内高功能甲状腺组织和多个放射性核素摄取增加(IRU)区域是良性甲状腺疾病的常见特征,对低剂量放射性碘治疗反应良好。