Fu Shijun, Sun Jianyi, Qian Lichun, Li Zhiyu
College of Animal Science, Zhejiang University, Hangzhou, 310029, People's Republic China.
Appl Biochem Biotechnol. 2008 Oct;151(1):1-8. doi: 10.1007/s12010-008-8158-7. Epub 2008 Feb 20.
Phytases are a special class of phosphatases that catalyze the sequential hydrolysis of phytate to less-phosphorylated myo-inositol derivatives and inorganic phosphate. Bacillus phytases, which exhibit their desirable activity profile under neutral pH, higher thermal stability, and strict substrate specificity for the calcium-phytate complex, have considerable potential in commercial and environmental applications. This review describes recent findings concerning the production, biochemical properties, molecular characteristics, and expression of Bacillus phytases. Several potential applications of the Bacillus phytases in animal nutrition, human health, and synthesis of lower myo-inositol phosphates are also summarized.
植酸酶是一类特殊的磷酸酶,可催化植酸依次水解为磷酸化程度较低的肌醇衍生物和无机磷酸盐。芽孢杆菌属植酸酶在中性pH条件下表现出理想的活性特征,具有较高的热稳定性,且对植酸钙复合物具有严格的底物特异性,在商业和环境应用中具有相当大的潜力。本综述描述了有关芽孢杆菌属植酸酶的生产、生化特性、分子特征和表达的最新研究结果。还总结了芽孢杆菌属植酸酶在动物营养、人类健康以及合成低磷酸化肌醇磷酸盐方面的一些潜在应用。