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三级医疗机构中接受治疗的高血压患者的血压控制情况

Blood pressure control among treated hypertensives in a tertiary health institution.

作者信息

Sani M U, Mijinyawa M S, Adamu B, Abdu A, Borodo M M

机构信息

Department of Medicine, Bayero University Kano, Aminu Kano Teaching Hospital Kano, Nigeria.

出版信息

Niger J Med. 2008 Jul-Aug;17(3):270-4. doi: 10.4314/njm.v17i3.37394.

Abstract

BACKGROUND

Goal blood pressure (BP) was defined by the JNC VI and the World Health Organization-International Society of Hypertension (WHO/ISH) as <140 mm Hg systolic and <90 mm Hg diastolic for the general and <130 mm Hg systolic and <85 mm Hg diastolic for special high-risk populations. It is well established that adequate BP control characterizes only a fraction of treated hypertensive patients. The importance of tight BP control has been established in preventing cardiovascular morbidity and mortality

METHODS

We performed cross-sectional studies on the current status of BP control among treated hypertensive in our center. One hundred consecutive patients with essential hypertension who have been attending the out patient hypertension clinic and have been on treatment for at least 6 months were recruited. The pre treatment BP and BP records in the previous 2 visits were noted. Patients were said to have good BP control if their BPs are < 140/90 mmHg (<130/80 mmHg for high risk patients) at the time of the study and in the last visit.

RESULTS

There were 49 males and 51 female (M: F; 1:1), aged 26 to 85 (mean 52.33 +/- 12.29) years. The duration of hypertension ranged 6 months to 30 (mean 7.37 +/- 7.1) years. The duration of treatment in our centre was 6 months to 10 (mean 3.22 +/- 2.23) years. Blood pressure was controlled in 33 (33%) of the patients. Pre-treatment mean blood pressure was significantly higher than the BP value at the time of the study (155.87 +/- 26.02/97.81 +/- 11.89 mmHg versus 143.40 +/- 24.14/86.53 +/- 12.71 mmHg) (p<0.05). Diuretics were the commonest antihypertensive prescribed either alone or in combination (69%), followed by a calcium antagonist (56%) and centrally acting drugs (38%). Twenty seven were on single antihypertensive, 43 (43%) on 2, 25(25%) on 3 and 5 (5%) on 4 classes of antihypertensive. Blood pressure control was associated with taking more than one antihypertensive medication and compliance.

CONCLUSION

Control of BP in patients receiving antihypertensive drugs is still far from optimal in the study population in Nigeria just as in other countries. Many patients had multiple cardiovascular risk factors. Adherence to medication should be encouraged.

摘要

背景

美国国立医学研究院第六次报告(JNC VI)以及世界卫生组织 - 国际高血压学会(WHO/ISH)将一般人群的目标血压定义为收缩压<140 mmHg,舒张压<90 mmHg;特殊高危人群的目标血压为收缩压<130 mmHg,舒张压<85 mmHg。众所周知,只有一部分接受治疗的高血压患者能实现血压的充分控制。严格控制血压对于预防心血管疾病的发病率和死亡率具有重要意义。

方法

我们对本中心接受治疗的高血压患者的血压控制现状进行了横断面研究。连续招募了100例原发性高血压患者,这些患者均在门诊高血压诊所就诊且接受治疗至少6个月。记录患者治疗前的血压以及前两次就诊时的血压记录。如果患者在研究时以及上次就诊时的血压<140/90 mmHg(高危患者<130/80 mmHg),则认为其血压控制良好。

结果

共有49例男性和51例女性(男:女 = 1:1),年龄在26至85岁之间(平均52.33±12.29岁)。高血压病程为6个月至30年(平均7.37±7.1年)。在本中心的治疗时间为6个月至10年(平均3.22±2.23年)。33例(33%)患者的血压得到控制。治疗前的平均血压显著高于研究时的血压值(155.87±26.02/97.81±11.89 mmHg对比143.40±24.14/86.53±12.71 mmHg)(p<0.05)。利尿剂是最常用的降压药,单独或联合使用的比例为69%,其次是钙拮抗剂(56%)和中枢性作用药物(38%)。27例患者使用单一降压药,43例(43%)使用两种,25例(25%)使用三种,5例(5%)使用四种降压药。血压控制与使用多种降压药物及依从性有关。

结论

与其他国家一样,在尼日利亚的研究人群中,接受降压药物治疗的患者的血压控制仍远未达到最佳状态。许多患者存在多种心血管危险因素。应鼓励患者坚持用药。

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