Uygur Fatih, Oncül Oral, Evinç Rahmi, Diktas Hüsrev, Acar Ali, Ulkür Ersin
Department of Plastic and Reconstructive Surgery and Burn Unit, Gülhane Military Medical Academy and Medical Faculty, Haydarpaşa Training Hospital, Selimiye Mahallesi Tibbiye Caddesi 34 668, Usküdar, Istanbul, Turkey.
Burns. 2009 Mar;35(2):270-3. doi: 10.1016/j.burns.2008.05.020. Epub 2008 Sep 11.
In this animal study, three topical antibacterial dressings, Acticoat, chlorhexidine acetate 0.5% and silver sulfadiazine 1%, were compared in the treatment of Acinetobacter baumannii contamination of burns. All treatments were effective and prevented the organism invading the muscle and causing systemic infection, so there were significant differences between the results of the treatment groups and the control group. Mean eschar concentrations did not differ significantly between the silver sulfadiazine and chlorhexidine acetate groups, but there were significant differences between these and the Acticoat group, indicating that Acticoat eliminated A. baumannii from the tissues more effectively.
在这项动物研究中，比较了三种局部抗菌敷料——Acticoat、0.5%醋酸氯己定和1%磺胺嘧啶银——用于治疗鲍曼不动杆菌烧伤感染的效果。所有治疗均有效，可防止病菌侵入肌肉并引发全身感染，因此治疗组与对照组的结果存在显著差异。磺胺嘧啶银组和醋酸氯己定组之间的平均焦痂浓度无显著差异，但这两组与Acticoat组之间存在显著差异，表明Acticoat能更有效地从组织中清除鲍曼不动杆菌。
