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三种国际指南对原发性自发性气胸大小分类的比较:是否需要国际共识?

Comparison of size classification of primary spontaneous pneumothorax by three international guidelines: a case for international consensus?

作者信息

Kelly Anne-Maree, Druda Dino

机构信息

Joseph Epstein Centre for Emergency Medicine Research, Western Health, St Albans 3021, Australia.

出版信息

Respir Med. 2008 Dec;102(12):1830-2. doi: 10.1016/j.rmed.2008.07.026. Epub 2008 Sep 11.

Abstract

OBJECTIVE

The aim of this study was to compare classification of pneumothoraces into size groups for treatment using the British Thoracic Society [BTS], American College of Chest Physicians [ACCP] and Belgian Society of Pulmonology [BSP] guidelines and the range of pneumothorax sizes in each group calculated using the volumetrically-derived Collins' method.

METHOD

This was a retrospective cohort study. Participants were patients with primary spontaneous pneumothorax [PSP] attending emergency departments of two teaching hospitals between 1996 and 2005. Participants were identified from a pre-existing database. Data collected included demographics, side of PSP and interpleural distances for size classification based on BTS, ACCP, BSP and Collins' method requirements measured on inspiratory X-rays. The outcome of interest was comparison of classification into size groups according to each guideline. Analysis was by descriptive statistics, overall agreement and Kappa analysis for agreement between guideline pairs.

RESULTS

Forty-nine episodes [44 patients] were studied. Median age was 22 years; 66% of patients were male. Median PSP size [Collins' method; inspiratory films] was 24%; range 5-100%. Based on inspiratory films, the BTS guideline classified 10% of PSP as large compared with 47% by the BSP guideline and 49% by the ACCP guideline. The three guidelines agreed in their classification in only 47% of cases.

CONCLUSION

Size classification of PSP based on available treatment guideline definitions shows poor agreement. This goes some way to explain management variation between regions and limits comparability of reported outcomes. There is a strong case for international agreement in size classification/estimation in order to facilitate high-quality studies into optimal management approaches.

摘要

目的

本研究旨在比较按照英国胸科学会(BTS)、美国胸科医师学会(ACCP)和比利时肺科学会(BSP)指南将气胸分为不同大小组以进行治疗的情况,以及使用体积推导的柯林斯方法计算的每组气胸大小范围。

方法

这是一项回顾性队列研究。研究对象为1996年至2005年间在两家教学医院急诊科就诊的原发性自发性气胸(PSP)患者。从一个现有的数据库中识别出研究对象。收集的数据包括人口统计学资料、PSP的患侧以及根据BTS、ACCP、BSP和柯林斯方法要求在吸气性X射线上测量的用于大小分类的胸膜腔间距。感兴趣的结果是根据各指南将气胸分为不同大小组的情况比较。分析采用描述性统计、总体一致性以及指南对之间一致性的kappa分析。

结果

研究了49例发作(44例患者)。中位年龄为22岁;66%的患者为男性。PSP的中位大小(柯林斯方法;吸气性胸片)为24%;范围为5%至100%。基于吸气性胸片,BTS指南将10%的PSP分类为大,而BSP指南为47%,ACCP指南为49%。这三种指南在仅47%的病例分类中达成一致。

结论

基于现有治疗指南定义的PSP大小分类显示出较差的一致性。这在一定程度上解释了不同地区管理的差异,并限制了所报告结果的可比性。为了促进对最佳管理方法的高质量研究,在大小分类/估计方面达成国际共识很有必要。

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