Ding D J
People's Hospital of Beijing Medical University.
Zhonghua Jie He He Hu Xi Za Zhi. 1991 Feb;14(1):19-21, 61-2.
In order to study the nature of chronic asthmatic bronchitis, we compared the clinical features of patients with chronic asthmatic bronchitis, bronchial asthma and simple chronic bronchitis. We also measured FEV1 on these patients before and after inhaling 1% isoproterenol aerosol as well as after administration of oral prednisone (40 mg/day) for a week. The results showed that there was little difference in terms of precipitating factors, attacking features, premonitory symptoms, developing course and relieving measures between the patients with chronic asthmatic bronchitis and bronchial asthma. The improved percentage of FEV1 (more than 15%) on the patients with chronic asthmatic bronchitis after inhalation of bronchodilator aerosol and administration of oral prednisone showed no significant difference from that of bronchial asthma. We suggest that the former term be replaced by the term of chronic bronchitis associated with asthma. It can probably avoid the confusion on the diagnosis of chronic bronchitis and bronchial asthma.
为了研究慢性喘息性支气管炎的本质,我们比较了慢性喘息性支气管炎、支气管哮喘和单纯慢性支气管炎患者的临床特征。我们还测量了这些患者吸入1%异丙肾上腺素气雾剂前后以及口服泼尼松(40毫克/天)一周后的第一秒用力呼气容积(FEV1)。结果显示,慢性喘息性支气管炎患者与支气管哮喘患者在诱发因素、发作特点、先兆症状、病程及缓解措施方面差异不大。慢性喘息性支气管炎患者吸入支气管扩张剂气雾剂和口服泼尼松后FEV1改善百分比(超过15%)与支气管哮喘患者相比无显著差异。我们建议将前一术语替换为哮喘相关性慢性支气管炎。这可能会避免慢性支气管炎和支气管哮喘诊断上的混淆。