己双肾上腺素气雾剂对支气管哮喘和慢性支气管炎的支气管扩张作用。

Bronchodilator effect of hexoprenaline aerosol in bronchial asthma and chronic bronchitis.

作者信息

Schonell M, Harris M, McMiken D, Jenne H, Evers R

出版信息

Med J Aust. 1977 Dec 17;2(25):828-30. doi: 10.5694/j.1326-5377.1977.tb99334.x.

DOI:10.5694/j.1326-5377.1977.tb99334.x

Abstract

The bronchodilator effects of aerosols of hexoprenaline (200 microgram and 400 microgram), and salbutamol (200 microgram) were compared in 15 patients with asthma, and nine patients with chronic bronchitis. In both groups of patients, hexoprenaline and salbutamol produced a similar increase in the forced expiratory volume in one second (FEV1), and mean percentage increase in FEV1. Neither drug caused tachycardia or arrhythmia. It was concluded that hexoprenaline aerosol was a safe and effective bronchodilator.

摘要

在15例哮喘患者和9例慢性支气管炎患者中，比较了己双肾上腺素气雾剂（200微克和400微克）和沙丁胺醇气雾剂（200微克）的支气管扩张作用。在两组患者中，己双肾上腺素和沙丁胺醇使一秒用力呼气量（FEV1）有相似的增加，FEV1的平均增加百分比也相似。两种药物均未引起心动过速或心律失常。得出的结论是，己双肾上腺素气雾剂是一种安全有效的支气管扩张剂。