Du B Y
Beijing Red Cross Chao Yang Hospital.
Zhonghua Jie He He Hu Xi Za Zhi. 1991 Apr;14(2):76-8, 126.
Our experiments were conducted on rabbits. In order to study the effects of passive smoking on the health, smokers were exposed to cigarette smoke for 30 days. Cigarette dosimetry is equivalent to two packs per day in man. The experimental results as follows. 1. There is a significant amount of Cotinine (0.69 microgram/ml) in the blood of passive smoking rabbits. 2. There is a lot of Benzpyrene (0.59 microgram/ml) in the BALF of passive smoking rabbits. 3. The level of histamine in BALF increased more than that of control group. 4. The level of TXB2 increased and the level of 6-keto-PGF1 alpha decreased in the blood of passive smoking rabbits more than that of the control group. 5. The level of elastase in the blood and the O2- production of alveolar macrophages of passive smoking rabbits are more than that of the control group. These results showed that passive smoking may increase the occurrence and development of COPD and cardiovascular disease as well.
我们的实验是在兔子身上进行的。为了研究被动吸烟对健康的影响，让吸烟者接触香烟烟雾30天。香烟剂量相当于人类每天两包。实验结果如下：1. 被动吸烟兔子的血液中存在大量可替宁（0.69微克/毫升）。2. 被动吸烟兔子的支气管肺泡灌洗液中存在大量苯并芘（0.59微克/毫升）。3. 支气管肺泡灌洗液中的组胺水平比对照组增加得更多。4. 被动吸烟兔子血液中的TXB2水平升高，6-酮-PGF1α水平比对照组下降得更多。5. 被动吸烟兔子血液中的弹性蛋白酶水平以及肺泡巨噬细胞的O2-生成量比对照组更多。这些结果表明，被动吸烟可能会增加慢性阻塞性肺疾病和心血管疾病的发生与发展。
