Perasole A, Infantolino D, Spigariol F
Servizio di Anatomia Patologica, Ospedale Civile di Montebelluna, Veneto, Italy.
Diagn Cytopathol. 1991;7(3):277-81. doi: 10.1002/dc.2840070313.
We present the cytologic features and immunocytochemical profile of a case of sacrococcygeal chordoma metastatic to the liver. Cytologic diagnosis was suspected from the aspiration biopsy smears of the primary sacrococcygeal tumor and confirmed by histology. Further aspirates failed to reveal diagnostic physaliferous cells, and only undifferentiated spindle cells were obtained. Chordoma may lack physaliferous cells: in such cases, immunocytochemistry studies can greatly facilitate the diagnosis. This study confirms the utility of immunocytochemistry in the differential diagnosis of chordoma and tumors with similar cytologic characteristics.
我们报告了一例骶尾部脊索瘤转移至肝脏病例的细胞学特征及免疫细胞化学图谱。通过对原发性骶尾部肿瘤的穿刺活检涂片怀疑有细胞学诊断，并经组织学证实。进一步的穿刺未能发现诊断性的空泡细胞，仅获得未分化的梭形细胞。脊索瘤可能缺乏空泡细胞：在这种情况下，免疫细胞化学研究可极大地有助于诊断。本研究证实了免疫细胞化学在脊索瘤与具有相似细胞学特征的肿瘤鉴别诊断中的作用。
