Huang F, Dambly-Chaudière C, Ghysen A
Laboratoire de Génétique, Université Libre de Bruxelles, Rhode-St-Genèse, Belgium.
Development. 1991 Apr;111(4):1087-95. doi: 10.1242/dev.111.4.1087.
We have examined the origin of a set of precisely located sense organs in the notum and wing of Drosophila, in transformant flies where lacZ is expressed in the progenitor cells of the sense organs (the sensory mother cells) and in their progeny. Here we describe the temporal pattern of appearance and divisions of the sensory mother cells that will form the eleven macrochaetes and the two trichoid sensilla of the notum, and five campaniform sensilla on the wing blade. The complete pattern of sensory mother cells develops in a strict sequence that extends over most of the third larval instar and the first 10 h after puparium formation. The delay between the onset of lacZ expression and the first differentiative division ranges from 30 h, in the case of the earliest mother cells, to 2 h for the latest mother cells. The first division shows a preferential orientation which is also specific for each sensory mother cell. Up to this stage, there is no marked difference between the three types of mechanosensory organs.
我们研究了果蝇背板和翅膀中一组精确定位的感觉器官的起源，这些果蝇是转基因果蝇，其中lacZ在感觉器官的祖细胞（感觉母细胞）及其后代中表达。在这里，我们描述了将形成背板的11个大刚毛和2个毛状感觉器以及翅片上5个钟形感觉器的感觉母细胞出现和分裂的时间模式。感觉母细胞的完整模式以严格的顺序发展，该顺序延伸到大部分第三龄幼虫期和化蛹后的前10小时。从最早的母细胞开始，lacZ表达开始与第一次分化分裂之间的延迟为30小时，而最晚的母细胞则为2小时。第一次分裂显示出一种优先取向，这对每个感觉母细胞也是特定的。到这个阶段，三种类型的机械感觉器官之间没有明显差异。
