Tsesis Igor, Faivishevsky Vadim, Fuss Zvi, Zukerman Ofer
Department of Endodontology, Maurice and Gabriela Goldschleger School of Dental Medicine, Tel Aviv University, Tel Aviv, Israel.
J Endod. 2008 Oct;34(10):1177-81. doi: 10.1016/j.joen.2008.07.016. Epub 2008 Aug 23.
The purpose of this study was to determine the frequency of flare-ups and to evaluate factors that affect it by using meta-analysis of results of previous studies. MEDLINE database was searched by using Entrez PubMed search engine and Medical Subject Headings (MeSH) search with EviDents Search Engine to identify the studies dealing with endodontic flare-up phenomenon. The search covered all articles published in dental journals in English from 1966-May 2007, and the relevancy of 119 selected articles was evaluated by reading their titles and abstracts, from which 54 were rejected as irrelevant and 65 were subjected to a suitability test. Six studies that met all the above mentioned criteria were included in the study. Average percentage of incidence of flare-ups for 982 patients was 8.4 (standard deviation +/-57). There were insufficient data to investigate the effect of the influencing factors.
本研究的目的是通过对既往研究结果进行荟萃分析，确定牙髓病急性发作的频率，并评估影响其发作的因素。使用Entrez PubMed搜索引擎和带有EviDents搜索引擎的医学主题词（MeSH）检索MEDLINE数据库，以识别有关牙髓病急性发作现象的研究。检索涵盖了1966年至2007年5月期间发表在英文牙科期刊上的所有文章，并通过阅读文章标题和摘要对119篇选定文章的相关性进行了评估，其中54篇因不相关而被排除，65篇接受了适用性测试。六项符合上述所有标准的研究被纳入本研究。982例患者急性发作的平均发生率为8.4%（标准差±57）。没有足够的数据来研究影响因素的作用。
