Postgraduate Program in Dentistry, University of Grande Rio (UNIGRANRIO), Rio de Janeiro, RJ, Brazil.
Department of Oral Medicine, Royal Portuguese Hospital of Charity in Pernambuco, Recife, PE, Brazil.
Clin Oral Investig. 2024 Aug 7;28(9):472. doi: 10.1007/s00784-024-05866-1.
The purpose of this prospective study was to evaluate the incidence and intensity of postoperative pain in oncological patients with infected teeth subjected to nonsurgical root canal treatment or retreatment.
Teeth with apical periodontitis from healthy control patients and oncological patients (n = 70 per group) were root canal treated/retreated and evaluated for the development of postoperative pain. Patients from the two groups were matched for tooth type, gender, clinical manifestation of apical periodontitis, and intervention type. A visual analogue scale (VSA) was used to evaluate the incidence of postoperative pain at 24 h, 72 h, 7d, and 15d after chemomechanical procedures. Data were statistically analyzed for the incidence and intensity of postoperative pain in the two groups.
Preoperative pain occurred in 10% of the individuals and in all these cases pain showed a reduction in intensity or was absent after endodontic intervention at 24-h evaluation. The overall incidence of postoperative pain at 24 h was 14% in oncology patients and 30% in controls (p = 0.03). At 72 h, the respective corresponding figures were 4% and 8.5% (p > 0.05). At 7 and 15 days, all patients were asymptomatic, irrespective of the group.
No significant differences in postoperative pain were found between control and oncological patients. The low incidence of postoperative pain observed in both groups supports the routine use of nonsurgical root canal treatment/retreatment as valid options in oncological patients.
Oncological patients had no increased risk of postoperative pain in comparison with control patients.
本前瞻性研究旨在评估行非手术根管治疗或再治疗的感染牙的肿瘤患者术后疼痛的发生率和强度。
健康对照组和肿瘤组患者(每组 70 颗牙)的根尖周炎牙接受根管治疗/再治疗,并评估术后疼痛的发生情况。两组患者的牙位、性别、根尖周炎临床表现和干预类型相匹配。采用视觉模拟评分(VAS)评估化学机械治疗后 24、72、7 和 15 天时的术后疼痛发生率。对两组患者的术后疼痛发生率和强度进行统计学分析。
10%的个体在术前出现疼痛,在所有这些情况下,疼痛在根管介入治疗后 24 小时评估时强度降低或消失。肿瘤患者术后疼痛的总发生率在 24 小时为 14%,对照组为 30%(p=0.03)。72 小时时,相应的数字分别为 4%和 8.5%(p>0.05)。7 和 15 天时,两组患者均无症状。
对照组和肿瘤患者之间的术后疼痛无显著差异。两组患者术后疼痛发生率均较低,支持非手术根管治疗/再治疗作为肿瘤患者的有效选择。
与对照组患者相比,肿瘤患者术后疼痛的风险无增加。