Videtic Gregory M M, Belderbos José S A, Spring Kong Feng-Ming, Kepka Lucyna, Martel Mary K, Jeremic Branislav
Department of Radiation Oncology, The Cleveland Clinic, Cleveland, OH 44195, USA.
Int J Radiat Oncol Biol Phys. 2008 Oct 1;72(2):327-34. doi: 10.1016/j.ijrobp.2008.03.075.
Thoracic radiotherapy (RT) is an integral part of the management of small-cell lung cancer (SCLC) because its administration provides a survival benefit in patients with limited-stage disease. However, there are many areas of controversy with respect to the delivery of curative RT, and these include definition of the target to be irradiated. A current area of concern is defining what the RT portal must encompass with respect to the mediastinal lymph nodes; that is, whether one should electively treat all mediastinal nodes, or selectively include those with some clinical risk for harboring disease, or perhaps omit elective nodal irradiation altogether. The purpose of the present report is therefore to address the concepts underlying elective or selective nodal irradiation as it applies to SCLC, looking at clinical, imaging, and RT reports to help define the parameters appropriate to treating individual patients.
胸部放疗（RT）是小细胞肺癌（SCLC）治疗不可或缺的一部分，因为对局限期疾病患者进行胸部放疗可带来生存获益。然而，在根治性放疗的实施方面存在许多争议领域，其中包括待照射靶区的定义。当前一个备受关注的领域是确定放疗射野对于纵隔淋巴结必须涵盖哪些范围；也就是说，是应选择性地对所有纵隔淋巴结进行治疗，还是有选择地纳入那些存在疾病风险的淋巴结，抑或是完全省略选择性淋巴结照射。因此，本报告的目的是探讨适用于SCLC的选择性或选择性淋巴结照射背后的概念，参考临床、影像学及放疗报告，以帮助确定适合治疗个体患者的参数。
