Requena Celia, Sanmartín Onofre, Requena Luis
Department of Dermatology, Instituto Valenciano de Oncología, 46009 Valencia, Spain.
Dermatol Clin. 2008 Oct;26(4):501-4, vii. doi: 10.1016/j.det.2008.06.001.
Sclerosing panniculitis is a chronic panniculitis characterized by skin induration and hyperpigmentation of one or both legs that often occurs in patients who have venous insufficiency. The indurated plaques are often painful and the legs frequently have a characteristic "inverted wine bottle" appearance. Histopathology is characterized by mostly lobular panniculitis with necrosis of fat and without vasculitis, and in fully developed lesions by septal sclerosis and membranocystic changes. Treatment of sclerosing panniculitis includes compression therapy with graded stockings and anabolic steroids.
硬化性脂膜炎是一种慢性脂膜炎，其特征为一条或两条腿出现皮肤硬结和色素沉着，常见于患有静脉功能不全的患者。硬结斑块通常疼痛，腿部常呈现特征性的“倒酒瓶”外观。组织病理学特征主要为小叶性脂膜炎伴脂肪坏死且无血管炎，在完全发展的病变中可见间隔硬化和膜性囊肿改变。硬化性脂膜炎的治疗包括使用分级弹力袜进行压迫治疗和使用合成代谢类固醇。
