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食管癌切除术后吻合口狭窄内镜扩张的最佳直径

Optimal diameter of endoscopic dilatation in anastomotic stricture after esophagectomy.

作者信息

Ryu Dae Gon, Choi Cheol Woong, Kim Su Jin, Park Su Bum, Jang Jin Ook, Kim Woo Jin, Son Bong Soo

机构信息

Department of Internal Medicine, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Beomeo-Ri Mulgeum-Eup, Yangsan, 50612, Gyeongsangnam-Do, Korea.

Department of Thoracic and Cardiovascular Surgery, Pusan National University School of Medicine and Research Institute for Convergence of Biomedical Science and Technology, Pusan National University Yangsan Hospital, Beomeo-Ri Mulgeum-Eup, Yangsan, 50612, Gyeongsangnam-Do, Korea.

出版信息

Surg Endosc. 2024 Dec;38(12):7253-7260. doi: 10.1007/s00464-024-11342-4. Epub 2024 Oct 11.

Abstract

BACKGROUND

The optimal diameter for endoscopic dilatation of anastomotic strictures after esophagectomy has not been elucidated. This study aimed to determine the optimal target diameter for endoscopic dilatation for anastomotic stricture after esophagectomy.

METHODS

The medical records of patients who underwent endoscopic dilatation for anastomotic stricture after esophagectomy between January 2009 and June 2024 at Pusan National University Yangsan Hospital were reviewed. The stricture recurrence rate, dilatation-free period, and complications according to the dilatation diameter were collected and included in the analysis.

RESULTS

We analyzed 149 endoscopic dilatations (diameters from 10 to 18 mm) in 43 patients. The median follow-up period was 47 months (range, 5-157). The stricture recurrence rate was 72.5%, and the median dilatation-free period was 60 days. The stricture recurrence rate was the lowest (41.7%, p = 0.022), and the overall dilatation-free period was the longest (median 490 days, p = 0.171) in dilations up to 16.5 mm. The stricture recurrence rate was higher in dilations up to 18 mm than in those up to 16.5 mm (54.5% vs. 41.7%, p = 0.331). Moreover, the bleeding rate was higher in patients with dilations up to 18 mm (18.2% vs. 4.2%, p = 0.205).

CONCLUSION

In patients with anastomotic strictures after esophagectomy, dilation up to 16.5 mm showed a lower stricture recurrence rate, longer dilation-free period, and less postprocedural bleeding than those of dilation up to 18 mm.

摘要

背景

食管癌切除术后吻合口狭窄内镜扩张的最佳直径尚未明确。本研究旨在确定食管癌切除术后吻合口狭窄内镜扩张的最佳目标直径。

方法

回顾了2009年1月至2024年6月在釜山国立大学杨山医院接受食管癌切除术后吻合口狭窄内镜扩张患者的病历。收集并分析了根据扩张直径的狭窄复发率、无扩张期和并发症情况。

结果

我们分析了43例患者的149次内镜扩张(直径为10至18毫米)。中位随访期为47个月(范围5至157个月)。狭窄复发率为72.5%,中位无扩张期为60天。在直径达16.5毫米的扩张中,狭窄复发率最低(41.7%,p = 0.022),总体无扩张期最长(中位490天,p = 0.171)。直径达18毫米的扩张的狭窄复发率高于直径达16.5毫米的扩张(54.5%对41.7%,p = 0.331)。此外,直径达18毫米的扩张患者的出血率更高(18.2%对4.2%,p = 0.205)。

结论

在食管癌切除术后吻合口狭窄患者中,与直径达18毫米的扩张相比,直径达16.5毫米的扩张显示出更低的狭窄复发率、更长的无扩张期和更少的术后出血。

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