Mullah-Ali Ali, Ramsay Jennifer A, Bourgeois Jacqueline M, Hodson Ian, Macdonald Paula, Midia Mehran, Portwine Carol
Departments of Pediatric Hematology/Oncology, Division of Pediatrics, McMaster University, Hamilton, Ontario, Canada.
J Pediatr Hematol Oncol. 2008 Jul;30(7):553-7. doi: 10.1097/MPH.0b013e31816e22e3.
The development of a soft-tissue sarcoma is an infrequent but well-known long-term complication of radiotherapy. Malignant fibrous histiocytomas, extraskeletal osteosarcomas, fibrosarcomas, malignant peripheral nerve sheath tumors, and angiosarcomas are most frequently encountered. Radiation-associated synovial sarcomas are uncommon and exceedingly rare in pediatric patients. We report an unusual case of paraspinal synovial sarcoma presenting in an adolescent female 13 years after radiation therapy for her neuroblastoma.
