Kably A, Meza E, Di Castro P, Villanueva C, Espinoza A, Serviere C, Alvarado A
Ginecol Obstet Mex. 1991 May;59:151-7.
It is a retrospective and transverse study with an analysis of results from patients submitted to intrauterine insemination (IIU), intratubal gamete transfer (GIFT) and in vitro fertilization and embryo transfer (FIVTE), at the Clinic of Assisted Reproduction, Instituto Nacional de Perinatología in Mexico City. From 134 cycles of patients submitted to IIU, 113 corresponded to women with diagnosis of sterility from non determined cause, and 21 to cases with endometriosis, and at least one permeable tube. From the first group, 22 pregnancies were obtained, for a monthly fertility rate of 19.4%; and from the second one, 12 pregnancies with a fertility rate of 56%. This, which is very high , may be explained by the relatively small number of cases in the second group, or else, by the influence of a previous medical treatment for endometriosis; the square Chi analysis shows a P less than 0.01 in the two groups. In the GIFT and FIVTE cases, from which 35 cycles were analyzed, per each procedure, there were 10 pregnancies, 9 for GIFT and one for FIVTE; the amount is very limited in order to obtain conclusions, but it seems that there is a proportional tendency in GIFT to less amount of pregnancies in women with endometriosis. The analysis of hormonal follow up did not show differences in the groups, and the averages may be useful to determine, early, the cancellation, or not, of an stimulation cycle. Finally, in FIVTE cases there is a diminution of fertilization index in women with endometriosis (53%), as compared with the cases without disease (80%).(ABSTRACT TRUNCATED AT 250 WORDS)
这是一项回顾性横断面研究，分析了墨西哥城国家围产医学研究所辅助生殖诊所接受宫内授精（IIU）、输卵管内配子移植（GIFT）以及体外受精和胚胎移植（FIVTE）的患者的结果。在134个接受IIU的患者周期中，113例为病因不明的不育女性，21例为子宫内膜异位症且至少有一条输卵管通畅的病例。第一组获得了22次妊娠，月受孕率为19.4%；第二组获得了12次妊娠，受孕率为56%。后者非常高，这可能是由于第二组病例数量相对较少，或者是由于先前对子宫内膜异位症的治疗影响；卡方分析显示两组的P值均小于0.01。在GIFT和FIVTE病例中，共分析了35个周期，每个程序有10次妊娠，GIFT为9次，FIVTE为1次；该数量非常有限，无法得出结论，但似乎GIFT中子宫内膜异位症女性的妊娠数量有减少的趋势。激素随访分析未显示各组之间存在差异，这些平均值可能有助于早期确定是否取消刺激周期。最后，在FIVTE病例中，与无疾病的病例（80%）相比，子宫内膜异位症女性的受精指数降低（53%）。（摘要截断于250字）
