Littman C D
Department of Pathology, University of Manitoba Health Sciences Centre, Winnipeg, Canada.
Histopathology. 1991 Jun;18(6):561-3. doi: 10.1111/j.1365-2559.1991.tb01485.x.
Primary malignant melanoma of the bronchus is an extremely rare neoplasm. The criteria required to establish a bronchial origin include junctional change and invasion of intact bronchial mucosa by melanoma cells. A case of metastatic melanoma demonstrating such changes is described, so casting doubt on the validity of these criteria.
原发性支气管恶性黑色素瘤是一种极为罕见的肿瘤。确立支气管起源所需的标准包括交界性改变以及黑色素瘤细胞对完整支气管黏膜的侵犯。本文描述了一例显示出此类改变的转移性黑色素瘤病例,从而对这些标准的有效性提出了质疑。